Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APAF1 | O14727 | 1/20 | 0.50 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.46 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3228613 | 0.81 | APAF1 (0.53) | APAF1LMNAMAPK1CYP2D6SRC | |
| SCHEMBL7127998 | 0.81 | APAF1 (0.53) | APAF1LMNAMAPK1CYP2D6SRC | |
| SCHEMBL7125053 | 0.81 | APAF1 (0.53) | APAF1LMNAMAPK1CYP2D6SRC | |
| SCHEMBL16486747 | 0.80 | PTGS2 (0.59) | APAF1MMEACE | |
| SCHEMBL23894335 | 0.79 | TRPA1 (0.57) | APAF1LMNAMAPK1CYP2D6SRC | |
| SCHEMBL12228632 | 0.79 | APAF1 (0.55) | APAF1LMNAMAPK1CYP2D6SRC | |
| SCHEMBL638421 | 0.78 | CYP1A2 (0.52) | CYP1A2MMEACE | |
| SCHEMBL2872818 | 0.77 | APAF1 (0.53) | APAF1LMNAMAPK1CYP2D6SRC | |
| SCHEMBL27580073 | 0.76 | TAAR1 (0.52) | APAF1LMNAMAPK1CYP2D6SRC | |
| SCHEMBL12191565 | 0.74 | APAF1 (0.50) | APAF1LMNAMAPK1CYP2D6SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101212985-A | Kinin antagonists for treating bladder dysfunction | JERINI AG (DE) | 2008-07-02 | — | — | CN | disclosed |
| EP-0597034-A4 | HAPTENS, TRACERS, IMMUNOGENS AND ANTIBODIES FOR IMMUNOASSAYS FOR PROPOXYPHENE. | ABBOTT LAB (US) | 1996-04-10 | — | — | EP | disclosed |
| EP-0597034-A1 | HAPTENS, TRACERS, IMMUNOGENS AND ANTIBODIES FOR IMMUNOASSAYS FOR PROPOXYPHENE | ABBOTT LABORATORIES (US) | 1994-05-18 | — | — | EP | disclosed |
| WO-1993003344-A2 | HAPTENS, TRACERS, IMMUNOGENS AND ANTIBODIES FOR IMMUNOASSAYS FOR PROPOXYPHENE | ABBOTT LABORATORIES (US) | 1993-02-18 | — | — | WO | disclosed |