SCHEMBL8935820

SCHEMBL8935820

NC(=O)CN1CCC[C@H]1C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 2/20 0.42
LMNA P02545 2/20 0.42
HSD17B10 Q99714 2/20 0.42
CYP1A2 P05177 1/20 0.41
ACE P12821 9/20 0.41
REN P00797 3/20 0.39
KDM4E B2RXH2 1/20 0.39
F2 P00734 1/20 0.39
LTA4H P09960 1/20 0.39
MAPT P10636 1/20 0.39
PEPD P12955 1/20 0.39
ALOX15 P16050 1/20 0.39
PTGS1 P23219 1/20 0.39
HTR2A P28223 1/20 0.39
PTGS2 P35354 1/20 0.39
HRH1 P35367 1/20 0.39
THPO P40225 1/20 0.39
PMP22 Q01453 1/20 0.39
ACE2 Q9BYF1 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6020595 1.00 CYP2C19 (0.42) CYP2C19LMNAHSD17B10CYP1A2ACE
Hydrochloric Acid SCHEMBL29025686 0.98 CYP2C19 (0.41) CYP2C19LMNAHSD17B10CYP1A2ACE
SCHEMBL1358371 0.85 TACR1 (0.37) CYP2C19LMNAHSD17B10CYP1A2ACE
SCHEMBL472181 0.84 ACE (0.45) CYP2C19LMNAHSD17B10CYP1A2ACE
SCHEMBL472180 0.84 ACE (0.45) CYP2C19LMNAHSD17B10CYP1A2ACE
SCHEMBL2177821 0.81 LMNA (0.46) CYP2C19LMNAHSD17B10CYP1A2ACE
SCHEMBL9110139 0.81 LMNA (0.46) CYP2C19LMNAHSD17B10CYP1A2ACE
SCHEMBL28452245 0.80 ACE (0.43) CYP2C19LMNAHSD17B10CYP1A2ACE
SCHEMBL17052427 0.80 ACE (0.43) CYP2C19LMNAHSD17B10CYP1A2ACE
SCHEMBL5509059 0.78 SMN1; SMN2 (0.46) CYP2C19LMNAHSD17B10CYP1A2ACE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4631573-A2 TEAD INHIBITORS Orion Corporation (FI) 2025-10-15 EP disclosed
EP-4323338-B1 TEAD INHIBITORS ORION CORP (FI) 2025-10-08 EP disclosed
CN-113768871-A Traditional Chinese medicine preparation of hydroxyl carthamin yellow A 陕西中医药大学 2021-12-10 CN disclosed
CN-111920881-A Plant extract with anti-saccharification effect 湖南朝露生物科技有限公司 2020-11-13 CN disclosed
EP-0601053-A4 COMPOSITIONS AND METHODS FOR THE SUBLINGUAL OR BUCCAL ADMINISTRATION OF THERAPEUTIC AGENTS. ABBOTT LAB (US) 1996-07-17 EP disclosed
EP-0601053-A1 COMPOSITIONS AND METHODS FOR THE SUBLINGUAL OR BUCCAL ADMINISTRATION OF THERAPEUTIC AGENTS ABBOTT LABORATORIES (US) 1994-06-15 EP disclosed
WO-1993003751-A1 COMPOSITIONS AND METHODS FOR THE SUBLINGUAL OR BUCCAL ADMINISTRATION OF THERAPEUTIC AGENTS ABBOTT LABORATORIES (US) 1993-03-04 WO disclosed
CN-1004920-B Process for preparing gonadotropin releasing hormone derivatives 克兹波特 1989-08-02 CN disclosed
CN-85101307-A The preparation method of gonadoliberin derivatives 1987-02-11 CN disclosed