Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 8/20 | 0.45 |
| ▸ | REN | P00797 | 3/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PEPD | P12955 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL472181 | 1.00 | ACE (0.45) | ACERENCYP2C19LMNAHSD17B10 | |
| SCHEMBL5509059 | 0.94 | SMN1; SMN2 (0.46) | ACERENCYP2C19LMNAHSD17B10 | |
| SCHEMBL2177821 | 0.84 | LMNA (0.46) | ACERENCYP2C19LMNAHSD17B10 | |
| SCHEMBL6020595 | 0.84 | CYP2C19 (0.42) | ACERENCYP2C19LMNAHSD17B10 | |
| SCHEMBL9110139 | 0.84 | LMNA (0.46) | ACERENCYP2C19LMNAHSD17B10 | |
| SCHEMBL8935820 | 0.84 | CYP2C19 (0.42) | ACERENCYP2C19LMNAHSD17B10 | |
| SCHEMBL27146149 | 0.84 | POLB (0.43) | ACERENCYP2C19LMNAHSD17B10 | |
| SCHEMBL27146148 | 0.84 | POLB (0.43) | ACERENCYP2C19LMNAHSD17B10 | |
| SCHEMBL28683755 | 0.84 | ACE (0.39) | ACERENCYP2C19LMNAHSD17B10 | |
| Hydrochloric Acid SCHEMBL29025686 | 0.82 | CYP2C19 (0.41) | ACERENCYP2C19LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046713-A2 | METHODS FOR PREPARING HETEROCYCLIC RINGS | ISIS INNOVATION (GB) | 2010-04-29 | — | — | WO | claimed |
| EP-2753702-B1 | CELL-FREE PREPARATION OF CARBAPENEMS | GREENLIGHT BIOSCIENCES INC (US) | 2021-12-15 | — | — | EP | disclosed |
| US-20210009508-A1 | Automated Synthesis of Small Molecules Using Chiral, Non-Racemic Boronates | NATIONAL SCIENCE FOUNDATION | 2021-01-14 | — | — | US | disclosed |
| US-10752577-B2 | Automated synthesis of small molecules using chiral, non-racemic boronates | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2020-08-25 | — | — | US | disclosed |
| US-20190315676-A1 | AUTOMATED SYNTHESIS OF SMALL MOLECULES USING CHIRAL, NON-RACEMIC BORONATES | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2019-10-17 | — | — | US | disclosed |
| WO-2019182440-A1 | METHOD FOR PRODUCING CELL WALL-TARGETING ANTIBIOTICS IN SUSCEPTIBLE BACTERIA | TECHNISCHE UNIVERSTITEIT DELFT (NL) | 2019-09-26 | — | — | WO | disclosed |
| US-10239824-B2 | Automated synthesis of small molecules using chiral, non-racemic boronates | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2019-03-26 | — | — | US | disclosed |
| US-20180312886-A1 | MICROBIAL PRODUCTION OF CHEMICAL PRODUCTS AND RELATED COMPOSITIONS, METHODS AND SYSTEMS | CARGILL INC (US) | 2018-11-01 | — | — | US | disclosed |
| US-20180312887-A1 | MICROBIAL PRODUCTION OF CHEMICAL PRODUCTS AND RELATED COMPOSITIONS, METHODS AND SYSTEMS | CARGILL INC (US) | 2018-11-01 | — | — | US | disclosed |
| WO-2018074916-A1 | METHODS FOR INCREASING PRODUCTION OF CARBAPENEM ANTIBIOTICS AND DERIVATIVES IN BACTERIA | TECHNISCHE UNIVERSITEIT DELFT (NL) | 2018-04-26 | — | — | WO | disclosed |
| EP-1446426-B1 | PEPTIDE PURIFICATION BY MEANS OF METAL ION AFFINITY CHROMATOGRAPHY | NOVO NORDISK AS (DK) | 2009-01-28 | — | — | EP | disclosed |
| US-20080293917-A1 | Peptide Purification By Means Of Metal Ion Affinity Chromatography | NOVO NORDISK A/S (DK) | 2008-11-27 | — | — | US | disclosed |
| US-7456276-B2 | Peptide purification by means of metal ion affinity chromatography | NOVO NORDISK A/S (DK) | 2008-11-25 | — | — | US | disclosed |
| US-7250456-B2 | Composition and its use for imparting water repellency to leather or furskins, textiles and other fibrous materials | TFL LEDERTECHNIK GMBH (DE) | 2007-07-31 | — | — | US | disclosed |
| US-20060287432-A1 | Peptide purification by means of metal ion affinity chromatography | NOVO NORDISK A/S (DK) | 2006-12-21 | — | — | US | disclosed |
| US-20050148702-A1 | Composition and its use for imparting water repellency to leather or furskins, textiles and other fibrous materials | TFL LEDERTECHNIK GMBH (DE) | 2005-07-07 | — | — | US | disclosed |
| EP-1470258-A1 | COMPOSITION AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS | TFL Ledertechnik GmbH (DE) | 2004-10-27 | — | — | EP | disclosed |
| EP-1446426-A2 | PEPTIDE PURIFICATION BY MEANS OF METAL ION AFFINITY CHROMATOGRAPHY | NOVO NORDISK A/S (DK) | 2004-08-18 | — | — | EP | disclosed |
| WO-2003064707-A1 | COMPOSITIONS AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS | TFL LEDERTECHNIK GMBH (DE) | 2003-08-07 | — | — | WO | disclosed |
| WO-2003042249-A2 | PEPTIDE PURIFICATION BY MEANS OF METAL ION AFFINITY CHROMATOGRAPHY | NOVO NORDISK A/S (DK) | 2003-05-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293917-A1 | Peptide Purification By Means Of Metal Ion Affinity Chromatography | NGLY1, VIP, NPPA | ACE 3181/4885REN 2569/4885CYP2C19 4863/4885 |
| US-10752577-B2 | Automated synthesis of small molecules using chiral, non-racemic boronates | BTD, POLL, POLR1A | ACE 837/4885REN 1984/4885CYP2C19 2078/4885 |
| US-20190315676-A1 | AUTOMATED SYNTHESIS OF SMALL MOLECULES USING CHIRAL, NON-RACEMIC BORONATES | BTD, POLL, POLR1A | ACE 837/4885REN 1984/4885CYP2C19 2078/4885 |
| US-10239824-B2 | Automated synthesis of small molecules using chiral, non-racemic boronates | BTD, POLL, POLR1A | ACE 837/4885REN 1984/4885CYP2C19 2078/4885 |
| US-20210009508-A1 | Automated Synthesis of Small Molecules Using Chiral, Non-Racemic Boronates | BTD, POLL, POLR1A | ACE 837/4885REN 1984/4885CYP2C19 2078/4885 |
| US-20060287432-A1 | Peptide purification by means of metal ion affinity chromatography | NGLY1, VIP, NPPA | ACE 3181/4885REN 2569/4885CYP2C19 4863/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.