Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.34 |
| ▸ | HTR2A | P28223 | 5/20 | 0.34 |
| ▸ | HTR2C | P28335 | 5/20 | 0.34 |
| ▸ | HTR2B | P41595 | 5/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8407916 | 0.77 | APP (0.50) | IDO1 | |
| SCHEMBL7627267 | 0.77 | IDO1 (0.42) | IDO1ALDH1A1CYP3A4 | |
| SCHEMBL7514298 | 0.76 | IDO1 (0.68) | IDO1SIGMAR1HTR2AHTR2CHTR2B | |
| SCHEMBL17710972 | 0.74 | KDM4E (0.57) | ALDH1A1CYP3A4ABCB1ALOX5 | |
| SCHEMBL15514435 | 0.72 | APP (0.55) | — | |
| SCHEMBL7785446 | 0.71 | ALDH1A1 (0.46) | IDO1SIGMAR1HTR2AHTR2CHTR2B | |
| SCHEMBL15515043 | 0.70 | IDO1 (0.48) | IDO1SIGMAR1HTR2AHTR2CHTR2B | |
| SCHEMBL9511296 | 0.70 | IDO1 (0.36) | IDO1ALDH1A1CYP3A4ABCB1ALOX5 | |
| SCHEMBL27677140 | 0.69 | CYP4F2 (0.43) | IDO1SIGMAR1HTR2AHTR2CHTR2B | |
| SCHEMBL1158123 | 0.68 | IDO1 (0.57) | IDO1SIGMAR1HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5589586-A | Nucleosides attached to a solid support through a 3'-silyl linkage and their use in oligonucleotide synthesis | PHARMACIA LKB BIOTECHNOLOGY AB (SE) | 1996-12-31 | — | — | US | disclosed |
| EP-0514513-B1 | METHOD AND MEANS FOR OLIGONUCLEOTIDE SYNTHESIS | PHARMACIA BIOTECH AB (SE) | 1996-01-31 | — | — | EP | disclosed |
| EP-0514513-A1 | METHOD AND MEANS FOR OLIGONUCLEOTIDE SYNTHESIS. | PHARMACIA LKB BIOTECH (SE) | 1992-11-25 | — | — | EP | disclosed |
| WO-1992009615-A1 | METHOD AND MEANS FOR OLIGONUCLEOTIDE SYNTHESIS | PHARMACIA LKB BIOTECHNOLOGY AB (SE) | 1992-06-11 | — | — | WO | disclosed |