Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 8/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | PPARG | P37231 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5063037 | 1.00 | PPARA (0.51) | PPARAALDH1A1SMN1; SMN2PPARGKMT2A | |
| SCHEMBL4370192 | 0.87 | SMN1; SMN2 (0.45) | PPARAALDH1A1SMN1; SMN2PPARGKMT2A | |
| SCHEMBL10877367 | 0.87 | PPARA (0.56) | PPARAALDH1A1PPARGKMT2AHPGD | |
| SCHEMBL28829280 | 0.86 | SMN1; SMN2 (0.48) | PPARAALDH1A1SMN1; SMN2PPARGLMNA | |
| SCHEMBL31698014 | 0.86 | SMN1; SMN2 (0.48) | PPARAALDH1A1SMN1; SMN2PPARGLMNA | |
| SCHEMBL31560857 | 0.84 | ALDH1A1 (0.49) | PPARAALDH1A1SMN1; SMN2KMT2AHPGD | |
| SCHEMBL1814149 | 0.83 | PPARA (0.51) | PPARAALDH1A1PPARGKMT2AHPGD | |
| SCHEMBL9322236 | 0.82 | CTRC (0.49) | PPARAALDH1A1PPARGSLC6A9 | |
| SCHEMBL11364459 | 0.81 | PPARA (0.50) | PPARAALDH1A1SMN1; SMN2PPARGKMT2A | |
| SCHEMBL8935688 | 0.81 | SMN1; SMN2 (0.49) | PPARASMN1; SMN2PPARGKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5491167-A | INHIBITORS OF CHOLESTEROL BIOSYNTHESIS | SANKYO COMPANY, LIMITED (JP) | 1996-02-13 | — | — | US | disclosed |