Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.46 |
| ▸ | PPARA | Q07869 | 11/20 | 0.46 |
| ▸ | PPARG | P37231 | 9/20 | 0.46 |
| ▸ | PLAU | P00749 | 2/20 | 0.36 |
| ▸ | FABP4 | P15090 | 1/20 | 0.36 |
| ▸ | PLG | P00747 | 1/20 | 0.36 |
| ▸ | PLAT | P00750 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8935919 | 1.00 | SMN1; SMN2 (0.49) | SMN1; SMN2PTPN1PPARAPPARGPLAU | |
| SCHEMBL17673228 | 0.84 | KMT2A (0.40) | SMN1; SMN2PTPN1PPARAPPARG | |
| SCHEMBL8935797 | 0.81 | PPARA (0.49) | SMN1; SMN2PTPN1PPARAPPARG | |
| SCHEMBL1245341 | 0.81 | PPARA (0.49) | SMN1; SMN2PTPN1PPARAPPARG | |
| SCHEMBL8935678 | 0.81 | SMN1; SMN2 (0.58) | SMN1; SMN2PPARAPPARG | |
| SCHEMBL8935675 | 0.81 | SMN1; SMN2 (0.58) | SMN1; SMN2PPARAPPARG | |
| Hydrochloric Acid SCHEMBL8074407 | 0.80 | PPARA (0.48) | SMN1; SMN2PTPN1PPARAPPARG | |
| SCHEMBL8935787 | 0.79 | SMN1; SMN2 (0.49) | SMN1; SMN2PPARAPPARG | |
| SCHEMBL8935688 | 0.79 | SMN1; SMN2 (0.49) | SMN1; SMN2PPARAPPARG | |
| SCHEMBL8935685 | 0.79 | SMN1; SMN2 (0.49) | SMN1; SMN2PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5491167-A | INHIBITORS OF CHOLESTEROL BIOSYNTHESIS | SANKYO COMPANY, LIMITED (JP) | 1996-02-13 | — | — | US | disclosed |