Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4955501 | 0.85 | LMNA (0.49) | LMNAALDH1A1NPSR1FOLH1CA2 | |
| SCHEMBL4955497 | 0.85 | LMNA (0.49) | LMNAALDH1A1NPSR1FOLH1CA2 | |
| SCHEMBL4955433 | 0.81 | LMNA (0.46) | LMNAALDH1A1NPSR1FOLH1CA2 | |
| SCHEMBL4955437 | 0.81 | LMNA (0.46) | LMNAALDH1A1NPSR1FOLH1CA2 | |
| SCHEMBL8185483 | 0.80 | LMNA (0.50) | LMNAALDH1A1NPSR1FOLH1CA2 | |
| SCHEMBL8185486 | 0.80 | LMNA (0.50) | LMNAALDH1A1NPSR1FOLH1CA2 | |
| SCHEMBL1298472 | 0.77 | LMNA (0.57) | LMNAALDH1A1NPSR1FOLH1CA2 | |
| SCHEMBL26090455 | 0.77 | LMNA (0.66) | LMNAALDH1A1NPSR1FOLH1CA2 | |
| SCHEMBL4326342 | 0.77 | LMNA (0.57) | LMNAALDH1A1NPSR1FOLH1CA2 | |
| SCHEMBL8400344 | 0.77 | SLC6A5 (0.46) | LMNAALDH1A1NPSR1FOLH1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5510530-A | WHEN POLYMERIZED GIVE OPTICALLY ACTIVE POLYMERS WHICH ARE USEFUL AS ADSORBENTS FOR CHROMATOGRAPHIC SEPARATION OF RACEMATES INTO ENANTIOMERS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-04-23 | — | — | US | disclosed |
| US-5432251-A | Acrylamide derivatives; use as polymeric adsorbent in separation of racemic mixtures into their optical antipodes | BAYER AKTIENGESELLSCHAFT (DE) | 1995-07-11 | — | — | US | disclosed |
| US-5432252-A | Acrylamide derivatives; use as polymeric adsorbent in separation of racemic mixtures into their optical antipodes | BAYER AKTIENGESELLSCHAFT (DE) | 1995-07-11 | — | — | US | disclosed |
| US-5347042-A | Optically active sulphur-containing amino acid derivatives, their preparation, their polymerisation to give optically active polymers and the use thereof | BAYER AKTIENGESELLSCHAFT (DE) | 1994-09-13 | — | — | US | disclosed |