SCHEMBL4326342

SCHEMBL4326342

CSCCC(NC(=O)O)C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.57
ALDH1A1 P00352 3/20 0.56
NPSR1 Q6W5P4 1/20 0.56
FOLH1 Q04609 1/20 0.51
CA2 P00918 2/20 0.50
MAPK1 P28482 2/20 0.50
USP2 O75604 2/20 0.50
RNPEP Q9H4A4 1/20 0.50
CA1 P00915 1/20 0.50
POLB P06746 1/20 0.50
TSHR P16473 1/20 0.50
GAA P10253 1/20 0.49
TP53 P04637 1/20 0.49
ALOX15 P16050 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1298472 1.00 LMNA (0.57) LMNAALDH1A1NPSR1FOLH1CA2
SCHEMBL28257478 0.98 LMNA (0.55) LMNAALDH1A1NPSR1FOLH1CA2
SCHEMBL26090455 0.88 LMNA (0.66) LMNAALDH1A1NPSR1FOLH1CA2
SCHEMBL109681 0.86 LMNA (0.55) LMNAALDH1A1NPSR1FOLH1CA2
SCHEMBL109682 0.86 LMNA (0.55) LMNAALDH1A1NPSR1FOLH1CA2
SCHEMBL109680 0.86 LMNA (0.55) LMNAALDH1A1NPSR1FOLH1CA2
SCHEMBL1332039 0.86 LMNA (0.55) LMNAALDH1A1NPSR1FOLH1CA2
SCHEMBL6091973 0.86 ALDH1A1 (0.44) LMNAALDH1A1NPSR1CA2MAPK1
SCHEMBL538038 0.84 LMNA (0.54) LMNAALDH1A1NPSR1FOLH1CA2
SCHEMBL2639626 0.84 LMNA (0.54) LMNAALDH1A1NPSR1FOLH1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111228511-B Anti-HER 3 antibody-drug conjugates 第一三共株式会社 2024-06-18 CN disclosed
EP-3681504-B1 METHODS OF DETECTION USING X-RAY FLUORESCENCE ICAGEN INC (US) 2023-08-23 EP disclosed
US-11573224-B2 Methods of detection using X-ray fluorescence ICAGEN, LLC (US) 2023-02-07 US disclosed
US-11446398-B2 Regulated biocircuit systems OBSIDIAN THERAPEUTICS, INC. (US) 2022-09-20 US disclosed
US-11209735-B2 Composition for forming metal-containing film, method of producing composition for forming metal-containing film, semiconductor device, and method of producing semiconductor device MITSUI CHEMICALS, INC. (JP) 2021-12-28 US disclosed
US-20210254056-A1 IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS CAMP4 THERAPEUTICS CORPORATION 2021-08-19 US disclosed
US-10877035-B2 Advanced drug development and manufacturing ICAGEN, LLC (US) 2020-12-29 US disclosed
US-20200278346-A1 METHODS OF DETECTION USING X-RAY FLUORESCENCE ADJACENT ACQUISITION CO., LLC 2020-09-03 US disclosed
EP-3681504-A1 METHODS OF DETECTION USING X-RAY FLUORESCENCE Icagen, Inc. (US) 2020-07-22 EP disclosed
US-20190192691-A1 REGULATED BIOCIRCUIT SYSTEMS OBSIDIAN THERAPEUTICS, INC. 2019-06-27 US disclosed
WO-2019055754-A1 METHODS OF DETECTION USING X-RAY FLUORESCENCE ICAGEN, INC. (US) 2019-03-21 WO disclosed
WO-2018204764-A1 IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS CAMP4 THERAPEUTICS CORPORATION (US) 2018-11-08 WO disclosed
US-20150309021-A1 Advanced Drug Development and Manufacturing LOS ALAMOS NATIONAL SECURITY, LLC 2015-10-29 US disclosed
EP-2511844-B1 X-ray microscope XRPRO SCIENCES INC (US) 2015-08-12 EP disclosed
EP-2511844-A2 Advanced drug development and manufacturing Los Alamos National Security, LLC (US) 2012-10-17 EP disclosed
EP-2084519-B1 X-RAY FLUORESCENCE ANALYSIS METHOD LOS ALAMOS NAT SECURITY LLC (US) 2012-08-01 EP disclosed
EP-2084519-A2 ADVANCED DRUG DEVELOPMENT AND MANUFACTURING Los Alamos National Security, LLC (US) 2009-08-05 EP disclosed
WO-2008127291-A2 ADVANCED DRUG DEVELOPMENT AND MANUFACTURING LOS ALAMOS NATIONAL SECURITY, LLC (US) 2008-10-23 WO disclosed
US-20080220441-A1 Advanced drug development and manufacturing THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2008-09-11 US disclosed