Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8936020 | 0.84 | LMNA (0.34) | RAB9ATP53MAPTHTTSMN1; SMN2 | |
| SCHEMBL8935998 | 0.76 | CA12 (0.33) | MAPTSMN1; SMN2LMNAGAA | |
| SCHEMBL10000161 | 0.69 | NPSR1 (0.46) | RAB9ATP53HTTSMN1; SMN2LMNA | |
| SCHEMBL30281258 | 0.65 | CA12 (0.45) | ALDH1A1CYP1A2 | |
| SCHEMBL25745097 | 0.65 | KMT2A (0.33) | LMNAALDH1A1HPGDKDM4E | |
| SCHEMBL22213898 | 0.61 | NPSR1 (0.45) | RAB9AHTTSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL6524605 | 0.61 | CYP1A2 (0.44) | MAPTHTTSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL23989782 | 0.61 | HIF1A (0.50) | RAB9ATP53HTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL195331 | 0.60 | — | — | |
| SCHEMBL8223259 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486531-A | ANGINA, HYPOTENSIVE AGENTS, ERECTILE DYSFUNCTION | CASSELLA AKTIENGESELLSCHAFT (DE) | 1996-01-23 | — | — | US | disclosed |