Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8936009 | 0.85 | GAA (0.37) | LMNAGAASMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL8936147 | 0.84 | RAB9A (0.32) | LMNAGAASMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL8935987 | 0.78 | GAA (0.33) | GAASMN1; SMN2ALDH1A1TP53NPC1 | |
| SCHEMBL8936008 | 0.76 | KCNH2 (0.35) | GAASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8936066 | 0.76 | GAA (0.31) | GAA | |
| SCHEMBL10000161 | 0.74 | NPSR1 (0.46) | LMNAGAASMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL8936001 | 0.71 | SMN1; SMN2 (0.37) | SMN1; SMN2ALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL23989782 | 0.69 | HIF1A (0.50) | GAASMN1; SMN2ALDH1A1TP53NPC1 | |
| SCHEMBL8936146 | 0.67 | ALDH1A1 (0.45) | LMNAGAASMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL8936123 | 0.66 | TP53 (0.40) | GAASMN1; SMN2TP53NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486531-A | ANGINA, HYPOTENSIVE AGENTS, ERECTILE DYSFUNCTION | CASSELLA AKTIENGESELLSCHAFT (DE) | 1996-01-23 | — | — | US | disclosed |