Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 4/20 | 0.33 |
| ▸ | CA1 | P00915 | 4/20 | 0.33 |
| ▸ | CA2 | P00918 | 4/20 | 0.33 |
| ▸ | CA9 | Q16790 | 4/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8936076 | 0.83 | GLA (0.44) | GLAMAPTSMN1; SMN2ALDH1A1HTT | |
| SCHEMBL2079547 | 0.79 | GLA (0.58) | GLAMAPTSMN1; SMN2ALDH1A1HTT | |
| SCHEMBL8785780 | 0.78 | GLA (0.33) | GLAMAPTSMN1; SMN2ALDH1A1HTT | |
| SCHEMBL8936017 | 0.74 | CATSPER1 (0.39) | GLAMAPTSMN1; SMN2ALDH1A1HTT | |
| SCHEMBL31094691 | 0.73 | GLA (0.48) | GLAMAPTSMN1; SMN2ALDH1A1HTT | |
| SCHEMBL429693 | 0.73 | CA12 (0.50) | GLAMAPTSMN1; SMN2ALDH1A1HTT | |
| SCHEMBL8785818 | 0.70 | GLA (0.38) | GLAMAPTSMN1; SMN2ALDH1A1HTT | |
| SCHEMBL8785463 | 0.68 | LMNA (0.36) | GLAMAPTSMN1; SMN2ALDH1A1HTT | |
| SCHEMBL8936040 | 0.67 | NPSR1 (0.42) | GLAMAPTSMN1; SMN2ALDH1A1HTT | |
| SCHEMBL11129701 | 0.67 | MAPT (0.36) | GLAMAPTSMN1; SMN2ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486531-A | ANGINA, HYPOTENSIVE AGENTS, ERECTILE DYSFUNCTION | CASSELLA AKTIENGESELLSCHAFT (DE) | 1996-01-23 | — | — | US | disclosed |