Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6346480 | 0.82 | GABRA1 (0.32) | GABRA1GABRB2ALDH1A1TSHR | |
| SCHEMBL10821929 | 0.78 | ALDH1A1 (0.39) | ALDH1A1TSHRPTGS1PTGS2 | |
| SCHEMBL311508 | 0.74 | GABRA1 (0.47) | GABRA1GABRB2ALDH1A1TSHRPTGS1 | |
| SCHEMBL19337408 | 0.73 | GABRA1 (0.50) | GABRA1GABRB2ALDH1A1TSHR | |
| SCHEMBL11357992 | 0.73 | GABRA1 (0.38) | GABRA1GABRB2ALDH1A1TSHRPTGS1 | |
| SCHEMBL394894 | 0.72 | GABRA1 (0.34) | GABRA1GABRB2 | |
| SCHEMBL10806052 | 0.72 | CA2 (0.48) | GABRA1GABRB2ALDH1A1TSHRPTGS1 | |
| SCHEMBL16628803 | 0.71 | ALDH1A1 (0.41) | ALDH1A1TSHR | |
| SCHEMBL5354598 | 0.68 | GABRA1 (0.34) | GABRA1GABRB2 | |
| SCHEMBL5352813 | 0.68 | GABRA1 (0.34) | GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5583188-A | USING TITANIUM, ORGANOALUMINUM, NITROGEN OR OXYGEN HETEROCYCLE CONTAINING CATALYST | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1996-12-10 | — | — | US | disclosed |
| EP-0227455-B1 | PROCESS FOR PRODUCING CATALYST INGREDIENT FOR USE IN OLEFIN POLYMERIZATION | Tonen Corporation (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4754006-A | Process for producing catalyst ingredient for use in olefin polymerization | TOA NENRYO KOGYO KABUSHIKI KAISHA (JP) | 1988-06-28 | — | — | US | disclosed |
| US-4737481-A | COORDINATION CATALYST CONTAINING MAGNESIUM DIALCOHOLATES, SILICON DI- OR TRI-HALIDES, TITANIUM HALIDES, ELECTRON DONORS | TOA NENRYO KOGYO KABUSHIKI KAISHA (JP) | 1988-04-12 | — | — | US | disclosed |
| EP-0227455-A2 | Process for producing catalyst ingredient for use in olefin polymerization | Tonen Corporation (JP) | 1987-07-01 | — | — | EP | disclosed |
| EP-0086644-B1 | CATALYST COMPOSITION AND PROCESS FOR POLYMERIZING OLEFINS | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1987-05-06 | — | — | EP | disclosed |
| EP-0187034-A2 | Process for producing poly-1-butene | TOA NENRYO KOGYO KABUSHIKI KAISHA (JP) | 1986-07-09 | — | — | EP | disclosed |
| EP-0086644-A2 | Catalyst composition and process for polymerizing olefins | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1983-08-24 | — | — | EP | disclosed |