Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA7 | P43166 | 3/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.41 |
| ▸ | IAPP | P10997 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28721957 | 0.85 | HSP90AB1 (0.58) | HSP90AB1PTGS2CYP3A4ACHECA12 | |
| Phloroglucinol SCHEMBL28315251 | 0.83 | TDP1 (0.59) | HSP90AB1PTGS2CYP3A4MEN1PTGS1 | |
| SCHEMBL8936444 | 0.79 | CTBP2 (0.53) | CYP3A4DRD3KMT2ALMNA | |
| SCHEMBL31618773 | 0.77 | IDH1 (0.40) | CYP3A4IAPPTDP1 | |
| SCHEMBL43309 | 0.77 | CA2 (0.58) | PTGS2CYP3A4MEN1PTGS1DRD3 | |
| SCHEMBL5703600 | 0.77 | PTGS2 (0.56) | HSP90AB1PTGS2CYP3A4MEN1KMT2A | |
| SCHEMBL27662921 | 0.77 | PTGS2 (0.56) | HSP90AB1PTGS2CYP3A4MEN1KMT2A | |
| SCHEMBL5703638 | 0.77 | PTGS2 (0.56) | HSP90AB1PTGS2CYP3A4MEN1KMT2A | |
| SCHEMBL27682613 | 0.77 | PTGS2 (0.56) | HSP90AB1PTGS2CYP3A4MEN1KMT2A | |
| SCHEMBL27682616 | 0.77 | PTGS2 (0.56) | HSP90AB1PTGS2CYP3A4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5512059-A | DYEING POLYUREHTANE ELASTIC FIBERS INCLUDING CHLORINE-INDUCED DEGRADATION INHIBITORS THAT DO NO ELUTE OUT | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 1996-04-30 | — | — | US | disclosed |
| US-5456960-A | A multicomponent yarn comprising a polyurethane elastic fiber containing one or more chlorination resistant inhibitors selected from the group consisting of oxides and hydroxides of magnesium, zinc, aluminum and hydrotalcite | TOYO BOSEKI KABUSHIHI KAISHA (JP) | 1995-10-10 | — | — | US | disclosed |
| EP-0489395-B1 | Dyed mixed knit fabric and method for its manufacture | TOYO BOSEKI (JP) | 1995-09-27 | — | — | EP | disclosed |
| EP-0489395-A1 | Dyed mixed knit fabric and method for its manufacture | Toyo Boseki Kabushiki Kaisha (JP) | 1992-06-10 | — | — | EP | disclosed |