Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | HTR1E | P28566 | 1/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
| ▸ | PARL | Q9H300 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5253993 | 0.78 | CCR2 (0.49) | KMT2AALDH1A1LMNA | |
| SCHEMBL963045 | 0.78 | MEN1 (0.42) | MEN1KMT2ACYP2C9ALDH1A1LMNA | |
| SCHEMBL26218806 | 0.75 | MAPT (0.49) | MAPTNPSR1HTR1ES1PR3MEN1 | |
| SCHEMBL26218807 | 0.74 | MAPT (0.48) | MAPTNPSR1HTR1ES1PR3MEN1 | |
| SCHEMBL19586439 | 0.73 | CRBN (0.51) | MEN1KMT2AACHEHSD17B10CYP3A4 | |
| SCHEMBL9110057 | 0.72 | HSD17B10 (0.48) | MAPTNPSR1HTR1ES1PR3MEN1 | |
| SCHEMBL512374 | 0.72 | MEN1 (0.44) | MEN1KMT2ACYP2C9ALDH1A1MMP2 | |
| SCHEMBL13093643 | 0.71 | HSD17B10 (0.44) | MAPTNPSR1HTR1ES1PR3MEN1 | |
| SCHEMBL9812380 | 0.71 | HSD17B10 (0.52) | MAPTNPSR1HTR1ES1PR3MEN1 | |
| SCHEMBL30480602 | 0.71 | ALDH1A1 (0.45) | MAPTCYP2C19ALDH1A1LMNAACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0637296-A4 | NON-STEROID PROGESTERONE RECEPTOR AGONIST AND ANTAGONIST COMPOUNDS AND METHODS. | LIGAND PHARM INC (US) | 1996-02-07 | — | — | EP | claimed |
| WO-1995011215-A1 | NON-STEROID ANDROGEN RECEPTOR ANTAGONISTS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 1995-04-27 | — | — | WO | claimed |
| EP-0637296-A1 | NON-STEROID PROGESTERONE RECEPTOR AGONIST AND ANTAGONIST COMPOUNDS AND METHODS | LIGAND PHARMACEUTICALS, INC. (US) | 1995-02-08 | — | — | EP | claimed |
| CN-116371466-B | Molecularly imprinted polymer modified magnetic immobilized tryptophan catalyst and preparation method and application thereof | 西安交通大学 | 2024-06-07 | — | — | CN | disclosed |
| CN-116371466-A | Molecularly imprinted polymer modified magnetic immobilized tryptophan catalyst and preparation method and application thereof | 西安交通大学 | 2023-07-04 | — | — | CN | disclosed |
| EP-0637296-A4 | NON-STEROID PROGESTERONE RECEPTOR AGONIST AND ANTAGONIST COMPOUNDS AND METHODS. | LIGAND PHARM INC (US) | 1996-02-07 | — | — | EP | disclosed |
| EP-0637296-A1 | NON-STEROID PROGESTERONE RECEPTOR AGONIST AND ANTAGONIST COMPOUNDS AND METHODS | LIGAND PHARMACEUTICALS, INC. (US) | 1995-02-08 | — | — | EP | disclosed |