Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 10/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8936542 | 0.91 | TACR1 (0.86) | TACR1SMN1; SMN2ALDH1A1KDM4ELMNA | |
| SCHEMBL8936429 | 0.89 | TACR1 (0.61) | TACR1SMN1; SMN2ALDH1A1KDM4ELMNA | |
| SCHEMBL8936576 | 0.82 | TACR1 (1.00) | TACR1SMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL8936577 | 0.82 | TACR1 (0.76) | TACR1ALDH1A1KMT2AMEN1 | |
| SCHEMBL8936508 | 0.81 | TACR1 (0.59) | TACR1ALDH1A1KDM4EHPGDPOLB | |
| SCHEMBL9178393 | 0.79 | TACR1 (0.57) | TACR1SMN1; SMN2KDM4ENPC1POLB | |
| SCHEMBL8936527 | 0.78 | TACR1 (0.90) | TACR1SMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL8936587 | 0.76 | TACR1 (0.64) | TACR1ALDH1A1KMT2AMEN1ADORA3 | |
| SCHEMBL8936439 | 0.76 | TACR1 (0.86) | TACR1SMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL8936454 | 0.76 | TACR1 (0.86) | TACR1ALDH1A1NPC1POLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5523305-A | ANALGESICS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-06-04 | — | — | US | disclosed |
| EP-0566069-A1 | Tachykinin receptor antagonists, isoquinolones and their production | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-10-20 | — | — | EP | disclosed |