Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 3/20 | 0.44 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11501075 | 0.75 | TLR7 (0.48) | EGFRLMNAHTTSMN1; SMN2TSHR | |
| SCHEMBL18083271 | 0.73 | KDM4E (0.64) | EGFRSMN1; SMN2TSHRKDM4EHSD17B10 | |
| SCHEMBL2776006 | 0.72 | KDM4E (0.62) | EGFRLMNAHTTSMN1; SMN2TSHR | |
| SCHEMBL9523615 | 0.72 | EGFR (0.48) | EGFRLMNAHTTSMN1; SMN2TSHR | |
| SCHEMBL18701233 | 0.71 | HSD17B10 (0.45) | EGFRLMNAHTTSMN1; SMN2TSHR | |
| SCHEMBL29186341 | 0.71 | MAOA (0.48) | LMNASMN1; SMN2TSHRMAOAPTPN1 | |
| SCHEMBL18083389 | 0.69 | HSD17B10 (0.62) | LMNAHTTSMN1; SMN2TSHRKDM4E | |
| SCHEMBL13436033 | 0.69 | SMN1; SMN2 (0.51) | EGFRLMNAHTTSMN1; SMN2TSHR | |
| SCHEMBL18701121 | 0.69 | SMN1; SMN2 (0.46) | EGFRLMNAHTTSMN1; SMN2TSHR | |
| SCHEMBL18701128 | 0.68 | KDM4E (0.53) | EGFRLMNASMN1; SMN2TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5576432-A | Process for the manufacture of dihydropyrimidines | EASTMAN KODAK COMPANY (US) | 1996-11-19 | — | — | US | disclosed |