Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.48 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16218259 | 0.82 | ALOX5 (0.57) | ALOX5RAB9AHPGDCYP1A2CYP2C19 | |
| SCHEMBL485998 | 0.79 | HPGD (0.64) | ALOX5RAB9AHPGDCYP1A2CYP2C19 | |
| SCHEMBL12085830 | 0.79 | HPGD (0.64) | ALOX5RAB9AHPGDCYP1A2CYP2C19 | |
| SCHEMBL17947424 | 0.79 | HPGD (0.64) | ALOX5RAB9AHPGDCYP1A2CYP2C19 | |
| SCHEMBL3963337 | 0.76 | HPGD (0.60) | ALOX5RAB9AHPGDCYP1A2CYP2C19 | |
| SCHEMBL6240188 | 0.75 | LOXL2 (0.62) | ALOX5RAB9AHPGDCYP1A2CYP2C19 | |
| SCHEMBL3060259 | 0.75 | ALOX5 (0.57) | ALOX5RAB9AHPGDCYP1A2CYP2C19 | |
| SCHEMBL11587666 | 0.75 | ALOX5 (0.65) | ALOX5RAB9AHPGDCYP1A2CYP2C19 | |
| SCHEMBL2146969 | 0.75 | LOXL2 (0.66) | ALOX5RAB9AHPGDCYP1A2CYP2C19 | |
| SCHEMBL62420 | 0.75 | LOXL2 (0.66) | ALOX5RAB9AHPGDCYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1042333-C | 5, 6-disubstituted-3-picolyl ammonium halide compound and preparation method thereof | AMERICAN CYANAMID CO (US) | 1999-03-03 | — | — | CN | disclosed |
| CN-1190094-A | Process of 5-(substituted methyl)-2,3-pyridinedicarboxylic acids | AMERICAN CYANAMID CO (US) | 1998-08-12 | — | — | CN | disclosed |
| US-5545835-A | CHEMICAL INTERMEDIATES FOR PREPARATION OF SUBSTITUTED 2,3-PYRIDINEDICARBOXYLIC ACIDS | AMERICAN CYANAMID COMPANY (US) | 1996-08-13 | — | — | US | disclosed |
| US-5378843-A | Halogenation, quaternization | AMERICAN CYANAMID COMPANY (US) | 1995-01-03 | — | — | US | disclosed |
| US-5288866-A | Chemical intermediates in the preparation of purity herbicides | AMERICAN CYANAMID COMPANY (US) | 1994-02-22 | — | — | US | disclosed |