Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 7/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | FNTA | P49354 | 1/20 | 0.40 |
| ▸ | FNTB | P49356 | 1/20 | 0.40 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8936690 | 0.84 | MEN1 (0.47) | ALDH1A1CYP19A1MEN1KMT2AGAA | |
| SCHEMBL8936771 | 0.83 | TDP1 (0.41) | CYP19A1MEN1KMT2ALMNATDP1 | |
| SCHEMBL9201309 | 0.76 | CCR1 (0.45) | CYP19A1LMNATDP1 | |
| SCHEMBL10581105 | 0.75 | ALDH1A1 (0.63) | ALDH1A1CYP19A1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL9194951 | 0.75 | FNTA (0.56) | CYP19A1MEN1KMT2ALMNAFNTA | |
| SCHEMBL8936766 | 0.75 | MAPT (0.41) | ALDH1A1CYP19A1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL5925434 | 0.73 | ALDH1A1 (0.47) | ALDH1A1CYP19A1MEN1KMT2ALMNA | |
| SCHEMBL9196269 | 0.73 | CYP19A1 (0.43) | ALDH1A1CYP19A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8936755 | 0.72 | PKM (0.41) | ALDH1A1CYP19A1MEN1KMT2ALMNA | |
| SCHEMBL9198771 | 0.72 | PKM (0.41) | CYP19A1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5587392-A | THERAPY FOR ESTROGEN DEPENDENT DISEASES | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-24 | — | — | US | disclosed |
| EP-0684235-A1 | Novel azolyl methyl phenyl derivatives having aromatase inhibitory activity | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-29 | — | — | EP | disclosed |