Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 7/20 | 0.40 |
| ▸ | NSD2 | O96028 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9204708 | 0.85 | CYP19A1 (0.44) | CYP19A1KDM4ESCN9ACYP11B1 | |
| SCHEMBL9201287 | 0.84 | CYP19A1 (0.39) | CYP19A1KDM4ESCN9ACYP11B1 | |
| SCHEMBL8936723 | 0.84 | CYP19A1 (0.39) | CYP19A1KDM4ESCN9ACYP11B1 | |
| SCHEMBL9202290 | 0.84 | CYP19A1 (0.39) | CYP19A1KDM4ECYP11B1 | |
| SCHEMBL8936774 | 0.83 | CYP19A1 (0.39) | CYP19A1NPSR1KDM4ESCN9ACYP11B1 | |
| SCHEMBL8936729 | 0.83 | CYP19A1 (0.41) | CYP19A1KDM4ECYP11B1 | |
| SCHEMBL8936742 | 0.83 | HCAR3 (0.43) | CYP19A1TDP1CYP11B1 | |
| SCHEMBL8936798 | 0.83 | CYP19A1 (0.39) | CYP19A1L3MBTL1TDP1CYP11B1 | |
| SCHEMBL8936780 | 0.81 | KDM4E (0.38) | CYP19A1KDM4ESCN9ACYP11B1 | |
| SCHEMBL8936761 | 0.81 | CYP19A1 (0.44) | CYP19A1SCN9ACYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5587392-A | THERAPY FOR ESTROGEN DEPENDENT DISEASES | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-24 | — | — | US | disclosed |
| EP-0684235-A1 | Novel azolyl methyl phenyl derivatives having aromatase inhibitory activity | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-29 | — | — | EP | disclosed |