Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 5/20 | 0.37 |
| ▸ | PDE2A | O00408 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.35 |
| ▸ | SELE | P16581 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8936798 | 0.89 | CYP19A1 (0.39) | CYP19A1MAPK1HPGDMAPTLMNA | |
| SCHEMBL8936742 | 0.89 | HCAR3 (0.43) | CYP19A1MAPK1HPGDTDP1CYP11B1 | |
| SCHEMBL9204708 | 0.82 | CYP19A1 (0.44) | CYP19A1MAPTLMNACYP11B1KDM4E | |
| SCHEMBL9202290 | 0.82 | CYP19A1 (0.39) | CYP19A1CYP11B1KDM4EHTT | |
| SCHEMBL9201287 | 0.82 | CYP19A1 (0.39) | CYP19A1MAPTCYP11B1KDM4E | |
| SCHEMBL8936723 | 0.82 | CYP19A1 (0.39) | CYP19A1MAPTCYP11B1KDM4E | |
| SCHEMBL8936722 | 0.82 | CYP19A1 (0.46) | CYP19A1MAPK1TDP1CYP11B1 | |
| SCHEMBL8936774 | 0.81 | CYP19A1 (0.39) | CYP19A1HPGDMAPTLMNACYP11B1 | |
| SCHEMBL8936729 | 0.80 | CYP19A1 (0.41) | CYP19A1MAPK1MAPTLMNACYP11B1 | |
| SCHEMBL8936685 | 0.79 | CYP19A1 (0.37) | CYP19A1MAPTCYP11B1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5587392-A | THERAPY FOR ESTROGEN DEPENDENT DISEASES | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-24 | — | — | US | disclosed |
| EP-0684235-A1 | Novel azolyl methyl phenyl derivatives having aromatase inhibitory activity | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-29 | — | — | EP | disclosed |