Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 5/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.55 |
| ▸ | ESRRA | P11474 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | RHEB | Q15382 | 1/20 | 0.42 |
| ▸ | SCN4A | P35499 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4441083 | 0.83 | SLC6A2 (0.64) | SLC6A2SLC6A4SLC6A3MEN1MAPT | |
| SCHEMBL4365850 | 0.81 | ALDH1A1 (0.58) | SLC6A2SLC6A4ESRRAMEN1KMT2A | |
| SCHEMBL7220532 | 0.81 | ESRRA (0.46) | ESRRAHPGDALDH1A1KDM4ECYP2A6 | |
| SCHEMBL11029113 | 0.81 | ESRRA (0.43) | ESRRAHPGDCYP1A2ALDH1A1CYP2A6 | |
| SCHEMBL807773 | 0.80 | SLC6A2 (0.59) | SLC6A2SLC6A4SLC6A3MEN1MAPT | |
| SCHEMBL8936781 | 0.77 | ESRRA (0.43) | SLC6A2SLC6A4SLC6A3ESRRAMEN1 | |
| Ethane SCHEMBL10636467 | 0.76 | HTR1B (0.50) | SLC6A4ESRRAMAPTL3MBTL1HPGD | |
| SCHEMBL442767 | 0.76 | HTR1B (0.54) | SLC6A4ESRRAMEN1MAPTKMT2A | |
| SCHEMBL29577853 | 0.76 | HTR1B (0.54) | SLC6A4ESRRAMEN1MAPTKMT2A | |
| SCHEMBL8936827 | 0.75 | HTT (0.67) | SLC6A2SLC6A4SLC6A3MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5587392-A | THERAPY FOR ESTROGEN DEPENDENT DISEASES | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-24 | — | — | US | disclosed |
| EP-0684235-A1 | Novel azolyl methyl phenyl derivatives having aromatase inhibitory activity | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-29 | — | — | EP | disclosed |