Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 20/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | UGT1A4 | P22310 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8936772 | 0.85 | CYP19A1 (0.47) | CYP19A1CYP11B1 | |
| SCHEMBL8936761 | 0.83 | CYP19A1 (0.44) | CYP19A1CYP11B1 | |
| SCHEMBL8936685 | 0.73 | CYP19A1 (0.37) | CYP19A1CYP11B1 | |
| SCHEMBL4245748 | 0.71 | SLC9A1 (0.48) | CYP19A1CYP11B1 | |
| SCHEMBL9204708 | 0.68 | CYP19A1 (0.44) | CYP19A1CYP11B1 | |
| SCHEMBL10584822 | 0.68 | CYP19A1 (0.56) | CYP19A1CYP11B1 | |
| SCHEMBL10584812 | 0.68 | CYP19A1 (0.56) | CYP19A1CYP11B1 | |
| SCHEMBL2285580 | 0.68 | CYP19A1 (1.00) | CYP19A1CYP11B1 | |
| SCHEMBL8936729 | 0.67 | CYP19A1 (0.41) | CYP19A1CYP11B1 | |
| SCHEMBL9201287 | 0.67 | CYP19A1 (0.39) | CYP19A1CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5587392-A | THERAPY FOR ESTROGEN DEPENDENT DISEASES | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-24 | — | — | US | disclosed |
| EP-0684235-A1 | Novel azolyl methyl phenyl derivatives having aromatase inhibitory activity | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-29 | — | — | EP | disclosed |