Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 5/20 | 0.62 |
| ▸ | FAAH | O00519 | 9/20 | 0.47 |
| ▸ | CES1 | P23141 | 6/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | FDPS | P14324 | 2/20 | 0.44 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.42 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.42 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6153272 | 0.94 | CES2 (0.53) | CES2FAAHCES1MEN1CYP1A2 | |
| SCHEMBL9067900 | 0.80 | FDPS (0.48) | CES2CES1FDPSSMPD1 | |
| SCHEMBL259016 | 0.76 | FDPS (0.48) | CES2MEN1KMT2AHSD17B10FDPS | |
| SCHEMBL27916871 | 0.76 | FDPS (0.48) | CES2FDPSSMPD1 | |
| SCHEMBL24276176 | 0.75 | CES2 (0.68) | CES2FAAHCES1MEN1CYP1A2 | |
| SCHEMBL31018949 | 0.74 | SMPD1 (0.50) | CES2MEN1KMT2AHSD17B10FDPS | |
| SCHEMBL287722 | 0.74 | SMPD1 (0.50) | CES2MEN1KMT2AHSD17B10FDPS | |
| SCHEMBL28842970 | 0.74 | FDPS (0.50) | CES2FDPSSMPD1 | |
| SCHEMBL1027737 | 0.74 | SMPD1 (0.50) | CES2MEN1KMT2AHSD17B10FDPS | |
| SCHEMBL20599006 | 0.74 | SMPD1 (0.50) | CES2MEN1KMT2AHSD17B10FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5563253-A | NON-RADIOACTIVE LABELLING | WORCESTER FOUNDATION FOR BIOMEDICAL RESEARCH (US) | 1996-10-08 | — | — | US | disclosed |
| US-5541306-A | LABELS | WORCESTER FOUNDATION FOR BIOMEDICAL RESEARCH (US) | 1996-07-30 | — | — | US | disclosed |
| US-5536821-A | Aminoalkylphosphorothioamidate oligonucleotide deratives | WORCESTER FOUNDATION FOR BIOMEDICAL RESEARCH (US) | 1996-07-16 | — | — | US | disclosed |
| US-5321131-A | Diagnosis, therapy | HYBRIDON, INC. (US) | 1994-06-14 | — | — | US | disclosed |
| WO-1991013902-A2 | SITE-SPECIFIC FUNCTIONALIZATION OF OLIGODEOXYNUCLEOTIDES FOR NON-RADIOACTIVE LABELLING | WORCESTER FOUNDATION FOR EXPERIMENTAL BIOLOGY (US) | 1991-09-19 | — | — | WO | disclosed |