Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.37 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.37 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.37 |
| ▸ | GSR | P00390 | 1/20 | 0.37 |
| ▸ | TLR2 | O60603 | 4/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.34 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.33 |
| ▸ | ERAP2 | Q6P179 | 3/20 | 0.32 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.32 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL663171 | 0.83 | KDM4E (0.42) | SIRT6SIRT1CA1CA2GNAI3 | |
| Sulfuric Acid SCHEMBL28324666 | 0.79 | GSR (0.53) | GNAI3GNAO1GNAI1GSRDPP8 | |
| SCHEMBL2257895 | 0.76 | KDM4E (0.36) | — | |
| SCHEMBL20240364 | 0.75 | GSR (0.61) | GNAI3GNAO1GNAI1GSRDPP8 | |
| SCHEMBL344574 | 0.75 | GSR (0.61) | GNAI3GNAO1GNAI1GSRDPP8 | |
| SCHEMBL1404247 | 0.75 | GSR (0.61) | GNAI3GNAO1GNAI1GSRDPP8 | |
| SCHEMBL11756660 | 0.74 | FOLH1 (0.51) | SIRT6SIRT1GSRITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL2099474 | 0.73 | GSR (0.59) | GNAI3GNAO1GNAI1GSRTLR2 | |
| SCHEMBL680614 | 0.73 | GSR (0.59) | GNAI3GNAO1GNAI1GSRDPP8 | |
| Hydrochloric Acid SCHEMBL3825519 | 0.73 | GSR (0.59) | GNAI3GNAO1GNAI1GSRTLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150231344-A1 | DRY POWDER INHALER SYSTEM | GALEPHAR PHARMACEUTICAL RESEARCH, INC. (US) | 2015-08-20 | — | — | US | claimed |
| EP-1658063-B1 | ADVANTAGEOUS COMBINATIONS FOR INHALATION OF NACYSTELYN AND BRONCHODILATORS | GALEPHAR M F (BE) | 2014-03-12 | — | — | EP | claimed |
| US-20100300440-A1 | Dry powder inhaler system | GALEPHAR P.R. INC. (BE) | 2010-12-02 | — | — | US | claimed |
| EP-1603615-B1 | IMPROVED DRY POWDER INHALER SYSTEM | GALEPHAR M F (BE) | 2008-07-09 | — | — | EP | claimed |
| US-20070071689-A1 | Advantageous combination for inhalation of nacystelyn and bronchodilators | GALEPHAR M/F (BE) | 2007-03-29 | — | — | US | claimed |
| US-20060254583-A1 | Dry powder inhaler system | GALEPHAR PHARMACEUTICAL RESEARCH, INC. (PR) | 2006-11-16 | — | — | US | claimed |
| US-7090870-B1 | Dry power inhaler excipient, process for its preparation and pharmaceutical compositions containing it | VANDERBIST FRANCIS | 2006-08-15 | — | — | US | claimed |
| EP-1658063-A1 | ADVANTAGEOUS COMBINATIONS FOR INHALATION OF NACYSTELYN AND BRONCHODILATORS | Galephar M/F (BE) | 2006-05-24 | — | — | EP | claimed |
| EP-1603615-A1 | IMPROVED DRY POWDER INHALER SYSTEM | Galephar M/F (BE) | 2005-12-14 | — | — | EP | claimed |
| US-20050154060-A1 | Anti-inflamatory inhalation pharmaceutical composition | GALEPHAR PHARMACEUTICAL RESEARCH, INC. (US) | 2005-07-14 | — | — | US | claimed |
| WO-2005013963-A1 | ADVANTAGEOUS COMBINATIONS FOR INHALATION OF NACYSTELYN AND BRONCHODILATORS | GALEPHAR M/F (BE) | 2005-02-17 | — | — | WO | claimed |
| WO-2004082750-A1 | IMPROVED DRY POWDER INHALER SYSTEM | GALEPHAR M/F (BE) | 2004-09-30 | — | — | WO | claimed |
| EP-0964675-B1 | DRY POWDER INHALER EXCIPIENT, PROCESS FOR ITS PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING IT | PHARLYSE SA (LU) | 2003-09-03 | — | — | EP | claimed |
| EP-0964675-A1 | DRY POWDER INHALER EXCIPIENT, PROCESS FOR ITS PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING IT | "PHARLYSE", Société Anonyme (LU) | 1999-12-22 | — | — | EP | claimed |
| WO-1998050015-A1 | DRY POWDER INHALER EXCIPIENT, PROCESS FOR ITS PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING IT | PHARLYSE, SOCIETE ANONYME (LU) | 1998-11-12 | — | — | WO | claimed |
| EP-0876814-A1 | Dry powder inhaler excipient, process for its preparation and pharmaceutical compositions containing it | "PHARLYSE", Société Anonyme (LU) | 1998-11-11 | — | — | EP | claimed |
| US-10709723-B2 | Pharmaceutical anti-infective composition for inhalation | GALEPHAR PHARMACEUTICAL RESEARCH, INC. (US) | 2020-07-14 | — | — | US | disclosed |
| EP-2083833-B1 | PHARMACEUTICAL ANTI-INFECTIVE COMPOSITION FOR INHALATION. | LABORATOIRES SMB SA (BE) | 2018-01-24 | — | — | EP | disclosed |
| WO-1998050015-A1 | DRY POWDER INHALER EXCIPIENT, PROCESS FOR ITS PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING IT | PHARLYSE, SOCIETE ANONYME (LU) | 1998-11-12 | — | — | WO | disclosed |
| EP-0876814-A1 | Dry powder inhaler excipient, process for its preparation and pharmaceutical compositions containing it | "PHARLYSE", Société Anonyme (LU) | 1998-11-11 | — | — | EP | disclosed |