Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 known ✓ | P27487 | 2/20 | 0.41 |
| ▸ | GSR | P00390 | 1/20 | 0.59 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.42 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.42 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.42 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 8/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.41 |
| ▸ | CPB2 | Q96IY4 | 3/20 | 0.41 |
| ▸ | ARG2 | P78540 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TLR2 | O60603 | 1/20 | 0.38 |
| ▸ | FAP | Q12884 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3825519 | 1.00 | GSR (0.59) | GSRGNAI3GNAO1GNAI1RNPEP | |
| Hydrochloric Acid SCHEMBL11287494 | 0.98 | GSR (0.57) | GSRGNAI3GNAO1GNAI1RNPEP | |
| Hydrochloric Acid SCHEMBL11287492 | 0.98 | GSR (0.57) | GSRGNAI3GNAO1GNAI1RNPEP | |
| SCHEMBL344574 | 0.98 | GSR (0.61) | GSRGNAI3GNAO1GNAI1RNPEP | |
| SCHEMBL20240364 | 0.98 | GSR (0.61) | GSRGNAI3GNAO1GNAI1RNPEP | |
| SCHEMBL1404247 | 0.98 | GSR (0.61) | GSRGNAI3GNAO1GNAI1RNPEP | |
| SCHEMBL680614 | 0.96 | GSR (0.59) | GSRGNAI3GNAO1GNAI1RNPEP | |
| Lysine SCHEMBL28806096 | 0.92 | GSR (0.74) | GSRRNPEPCPB2ARG2BLM | |
| SCHEMBL16194521 | 0.91 | GSR (0.59) | GSRGNAI3GNAO1GNAI1RNPEP | |
| SCHEMBL997560 | 0.91 | GSR (0.52) | GSRGNAI3GNAO1GNAI1RNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57045145-A | — | — | None | — | — | JP | disclosed |
| CN-112679371-B | Preparation method of L-lysine hydrochloride beta crystal form | 北京民康百草医药科技有限公司 | 2022-11-18 | — | — | CN | disclosed |
| CN-112679371-A | Preparation method of L-lysine hydrochloride beta crystal form | 北京民康百草医药科技有限公司 | 2021-04-20 | — | — | CN | disclosed |
| EP-2096176-B1 | METHOD OF OBTAINING CRYSTAL OF HYDROCHLORIDE OF BASIC AMINO ACID | AJINOMOTO KK (JP) | 2017-04-12 | — | — | EP | disclosed |
| US-8372606-B2 | Methods for obtaining crystals of a basic amino acid hydrochloride | AJINOMOTO CO., INC. (JP) | 2013-02-12 | — | — | US | disclosed |
| CN-101558164-B | Method for obtaining crystals of hydrochloride of basic amino acid | AJINOMOTO KK | 2012-05-09 | — | — | CN | disclosed |
| US-8163865-B2 | Biocompatible amino acid anhydride polymers | UNIVERSITY OF WASHINGTON (US) | 2012-04-24 | — | — | US | disclosed |
| US-20100015205-A1 | BIOCOMPATIBLE AMINO ACID ANHYDRIDE POLYMERS | WASHINGTON, UNIVERSITY OF (US) | 2010-01-21 | — | — | US | disclosed |
| US-20090291477-A1 | METHODS FOR OBTAINING CRYSTALS OF A BASIC AMINO ACID HYDROCHLORIDE | AJINOMOTO CO., INC. (JP) | 2009-11-26 | — | — | US | disclosed |
| CN-101558164-A | Method of obtaining crystal of hydrochloride of basic amino acid | AJINOMOTO KK (JP) | 2009-10-14 | — | — | CN | disclosed |
| EP-2096176-A1 | METHOD OF OBTAINING CRYSTAL OF HYDROCHLORIDE OF BASIC AMINO ACID | Ajinomoto Co., Inc. (JP) | 2009-09-02 | — | — | EP | disclosed |
| WO-2008098220-A1 | BIOCOMPATILE AMINO ACID ANHYDRIDE POLYMERS | UNIVERSITY OF WASHINGTON (US) | 2008-08-14 | — | — | WO | disclosed |
| EP-1035109-B1 | Aqueous lysine solution | AJINOMOTO KK (JP) | 2005-05-11 | — | — | EP | disclosed |
| US-20040214895-A1 | Aqueous stable lysine solution | AJINOMOTO CO., INC. (JP) | 2004-10-28 | — | — | US | disclosed |
| US-20020123648-A1 | Aqueous stable lysine solution | AJINOMOTO CO., INC. (JP) | 2002-09-05 | — | — | US | disclosed |
| US-6329548-B1 | FEED ADDITIVE FOR PRODUCING A FEED FOR DOMESTIC ANIMALS SUCH AS CATTLE, PIGS AND CHICKENS | AJINOMOTO CO., INC. (JP) | 2001-12-11 | — | — | US | disclosed |
| US-20010043942-A1 | Aqueous stable lysine solution | AJINOMOTO, CO., INC. (JP) | 2001-11-22 | — | — | US | disclosed |
| EP-1035109-A1 | Aqueous lysine solution | Ajinomoto Co., Inc. (JP) | 2000-09-13 | — | — | EP | disclosed |
| JP-S5745145-A | PREPARATION OF PACKAGED LYSINE HYCROCHLORIDE | AJINOMOTO CO INC | 1982-03-13 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100015205-A1 | BIOCOMPATIBLE AMINO ACID ANHYDRIDE POLYMERS | CRYAA, FIBP, LNPEP | DPP4 1549/4885GSR 3746/4885GNAI3 2885/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.