Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Ethanesulfonic Acid Amide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 11/20 | 0.50 |
| ▸ | CA1 | P00915 | 10/20 | 0.50 |
| ▸ | CA5A | P35218 | 3/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.50 |
| ▸ | CA9 | Q16790 | 3/20 | 0.50 |
| ▸ | CA4 | P22748 | 2/20 | 0.50 |
| ▸ | CA6 | P23280 | 2/20 | 0.50 |
| ▸ | CA7 | P43166 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NT5E | P21589 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethanesulfonic Acid Amide SCHEMBL28038 | 0.88 | — | — | |
| Ethanesulfonic Acid Amide SCHEMBL27416092 | 0.84 | — | — | |
| Ethanesulfonic Acid Amide SCHEMBL3480490 | 0.84 | — | — | |
| Ethanesulfonic Acid Amide SCHEMBL27765064 | 0.84 | — | — | |
| Ethanesulfonic Acid Amide SCHEMBL9859651 | 0.84 | — | — | |
| Ethanesulfonic Acid Amide SCHEMBL27673482 | 0.84 | — | — | |
| Ethanesulfonic Acid Amide SCHEMBL1996587 | 0.84 | — | — | |
| Ethanesulfonic Acid Amide SCHEMBL3402460 | 0.84 | — | — | |
| Ethanesulfonic Acid Amide SCHEMBL2883670 | 0.84 | — | — | |
| Ethanesulfonic Acid Amide SCHEMBL27765538 | 0.83 | LMNA (0.50) | CA2CA1CA5ACA5BCA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0090610-B1 | A METHOD FOR TREATMENT OF MUTAGENS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-07-01 | — | — | EP | claimed |
| US-4460475-A | Method for treatment of mutagens | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-07-17 | — | — | US | claimed |
| EP-0090610-A2 | A method for treatment of mutagens | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-10-05 | — | — | EP | claimed |
| JP-8170278-A | — | — | None | — | — | JP | disclosed |
| CN-102448550-A | Compositions for reducing transmission of human pathogens | FILLIGENT LTD | 2012-05-09 | — | — | CN | disclosed |
| JP-H08170278-A | METHOD FOR DYEING CLOTH, PRINTING PASTE AND DYED CLOTH | KIMURA SHOJI KK | 1996-07-02 | — | — | JP | disclosed |
| EP-0090610-B1 | A METHOD FOR TREATMENT OF MUTAGENS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-07-01 | — | — | EP | disclosed |
| US-4460475-A | Method for treatment of mutagens | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-07-17 | — | — | US | disclosed |
| EP-0090610-A2 | A method for treatment of mutagens | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-10-05 | — | — | EP | disclosed |