Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | S100A4 | P26447 | 2/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.40 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.40 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.40 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.40 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6049656 | 0.83 | DHFR (0.50) | PTPRCMAPTKMT2AMEN1HPGD | |
| SCHEMBL8937640 | 0.73 | PDE7A (0.39) | MAPTKMT2AMEN1HPGDPDE7A | |
| SCHEMBL21223480 | 0.69 | NUDT1 (0.45) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL21223471 | 0.69 | FEN1 (0.48) | ADRA1A | |
| SCHEMBL435495 | 0.68 | PTPRC (0.85) | PTPRCMAPTKMT2AMEN1S100A4 | |
| SCHEMBL9755024 | 0.66 | PTPRC (0.62) | PTPRCMAPTKMT2AMEN1S100A4 | |
| SCHEMBL21223655 | 0.65 | EPHB4 (0.51) | HSP90AA1 | |
| SCHEMBL7607907 | 0.65 | PDE7A (0.55) | PTPRCMAPTKMT2AMEN1S100A4 | |
| SCHEMBL10487196 | 0.65 | CYP3A4 (0.64) | PTPRCMAPTKMT2AMEN1S100A4 | |
| Hydrochloric Acid SCHEMBL21223661 | 0.64 | EPHB4 (0.50) | HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5587380-A | ANTIISCHEMIC AGENTS | GLAXO WELLCOME INC. (US) | 1996-12-24 | — | — | US | disclosed |