Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 4/20 | 0.39 |
| ▸ | DHFR | P00374 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6049654 | 0.81 | DHFR (0.55) | DHFRMAPTHPGDMEN1KMT2A | |
| SCHEMBL8937642 | 0.73 | PTPRC (0.44) | PDE7AMAPTHPGDMEN1KMT2A | |
| SCHEMBL16174634 | 0.72 | S100A4 (0.50) | PDE7AMAPTHPGDMEN1KMT2A | |
| SCHEMBL3259771 | 0.69 | ADORA2A (0.38) | PDE7AMAPTHPGDMEN1KMT2A | |
| SCHEMBL18967848 | 0.68 | S100A4 (0.56) | MAPTHPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL16663608 | 0.67 | ALDH1A1 (0.49) | PDE7ADHFRMAPTMEN1KMT2A | |
| SCHEMBL29563051 | 0.67 | ALDH1A1 (0.49) | PDE7ADHFRMAPTMEN1KMT2A | |
| SCHEMBL57031 | 0.67 | ALDH1A1 (0.49) | PDE7ADHFRMAPTMEN1KMT2A | |
| SCHEMBL11901405 | 0.67 | S100A4 (0.50) | PDE7AMAPTHPGDKMT2AALDH1A1 | |
| SCHEMBL10714006 | 0.67 | ALDH1A1 (0.51) | PDE7AMAPTHPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5587380-A | ANTIISCHEMIC AGENTS | GLAXO WELLCOME INC. (US) | 1996-12-24 | — | — | US | disclosed |