Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 6/20 | 1.00 |
| ▸ | PTPRC | P08575 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | FDPS | P14324 | 1/20 | 0.37 |
| ▸ | POLA1 | P09884 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8938035 | 0.81 | ACP3 (0.67) | ACP3MEN1ALDH1A1KMT2AKDM4E | |
| SCHEMBL3346090 | 0.76 | ACP3 (0.61) | ACP3PTPRCMEN1KMT2AKDM4E | |
| Butane SCHEMBL8938014 | 0.70 | ACP3 (0.54) | ACP3MEN1ALDH1A1KMT2ACYP1A2 | |
| SCHEMBL8938015 | 0.70 | ACP3 (0.53) | ACP3MEN1ALDH1A1KMT2AKDM4E | |
| SCHEMBL10860781 | 0.69 | ACP3 (0.57) | ACP3PTPRCMEN1KMT2ACYP1A2 | |
| SCHEMBL341944 | 0.69 | PTPRC (0.69) | ACP3PTPRCMEN1KMT2AKDM4E | |
| SCHEMBL10881272 | 0.67 | FDPS (0.69) | ACP3ALDH1A1MAPTFDPS | |
| SCHEMBL11762883 | 0.65 | ACP3 (0.48) | ACP3PTPRCMEN1ALDH1A1KMT2A | |
| SCHEMBL8938043 | 0.65 | ACP3 (0.54) | ACP3MEN1ALDH1A1KMT2ACYP1A2 | |
| SCHEMBL8376830 | 0.64 | ACP3 (0.45) | ACP3MEN1ALDH1A1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5508273-A | ARALKYLPHOSPHONATES FOR OSTEOPOROSIS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1996-04-16 | — | — | US | disclosed |