Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8938035 | 0.79 | ACP3 (0.67) | ACP3HPGDKDM4ELMNAALDH1A1 | |
| Butane SCHEMBL8938014 | 0.74 | ACP3 (0.54) | ACP3HPGDKDM4EALDH1A1MEN1 | |
| SCHEMBL8938007 | 0.70 | ACP3 (1.00) | ACP3HPGDKDM4EALDH1A1MEN1 | |
| SCHEMBL28082905 | 0.66 | HPGD (0.51) | HPGDKDM4ELMNAALDH1A1THRB | |
| SCHEMBL917064 | 0.64 | NPY5R (0.42) | KDM4EALDH1A1THRBMEN1MAPT | |
| SCHEMBL27680889 | 0.64 | TSHR (0.48) | HPGDKDM4EALDH1A1THRBL3MBTL1 | |
| SCHEMBL28082907 | 0.64 | HPGD (0.49) | HPGDKDM4ELMNAALDH1A1THRB | |
| SCHEMBL8938043 | 0.63 | ACP3 (0.54) | ACP3HPGDKDM4ELMNAALDH1A1 | |
| SCHEMBL1773883 | 0.63 | ACP3 (0.57) | ACP3HPGDKDM4ELMNAALDH1A1 | |
| SCHEMBL8938008 | 0.62 | ACP3 (0.50) | ACP3HPGDKDM4ELMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5508273-A | ARALKYLPHOSPHONATES FOR OSTEOPOROSIS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1996-04-16 | — | — | US | disclosed |