Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 2/20 | 0.67 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8938007 | 0.81 | ACP3 (1.00) | ACP3HPGDKDM4EALDH1A1KMT2A | |
| SCHEMBL8938015 | 0.79 | ACP3 (0.53) | ACP3HPGDKDM4ELMNAALDH1A1 | |
| Butane SCHEMBL8938014 | 0.71 | ACP3 (0.54) | ACP3HPGDKDM4EALDH1A1KMT2A | |
| SCHEMBL8832067 | 0.67 | HPGD (0.46) | ACP3HPGDKDM4ELMNAALDH1A1 | |
| SCHEMBL8938043 | 0.66 | ACP3 (0.54) | ACP3HPGDKDM4ELMNAALDH1A1 | |
| SCHEMBL3346090 | 0.66 | ACP3 (0.61) | ACP3HPGDKDM4ELMNAL3MBTL1 | |
| SCHEMBL5580152 | 0.64 | DRD4 (0.49) | ACP3HPGDALDH1A1THRBL3MBTL1 | |
| SCHEMBL10631805 | 0.63 | KDM4E (0.54) | HPGDKDM4ELMNAALDH1A1HTT | |
| SCHEMBL28223073 | 0.63 | KDM4E (0.54) | HPGDKDM4ELMNAALDH1A1HTT | |
| SCHEMBL518217 | 0.62 | POLB (0.44) | HPGDKDM4ELMNAALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5508273-A | ARALKYLPHOSPHONATES FOR OSTEOPOROSIS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1996-04-16 | — | — | US | disclosed |