Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | ACMSD | Q8TDX5 | 3/20 | 0.39 |
| ▸ | HNF4A | P41235 | 2/20 | 0.39 |
| ▸ | DHFR | P00374 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ESR1 | P03372 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1451004 | 0.98 | ALDH1A1 (0.43) | ALOX5ALDH1A1ACMSDHNF4ADHFR | |
| SCHEMBL1535844 | 0.95 | ALDH1A1 (0.38) | ALOX5ALDH1A1ACMSDHNF4ADHFR | |
| SCHEMBL18221938 | 0.91 | ALDH1A1 (0.38) | ALOX5ALDH1A1ACMSDHNF4ADHFR | |
| SCHEMBL15067523 | 0.91 | ALDH1A1 (0.45) | ALOX5ALDH1A1ACMSDHNF4ADHFR | |
| SCHEMBL9706195 | 0.90 | NPC1 (0.41) | ALDH1A1MCL1MEN1KMT2AMAPT | |
| SCHEMBL7995315 | 0.90 | HSD17B10 (0.56) | ALOX5ALDH1A1ACMSDHNF4ADHFR | |
| SCHEMBL7455536 | 0.90 | FLT3 (0.39) | ALOX5MEN1KMT2AESR2TAAR1 | |
| SCHEMBL2341383 | 0.90 | MMP3 (0.56) | ALOX5ACMSDHNF4ADHFRMCL1 | |
| SCHEMBL7703865 | 0.87 | GSTP1 (0.44) | MCL1MAOAMEN1KMT2ABCL2L1 | |
| SCHEMBL21635205 | 0.86 | HSD17B1 (0.47) | ALOX5ALDH1A1ACMSDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5508273-A | ARALKYLPHOSPHONATES FOR OSTEOPOROSIS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1996-04-16 | — | — | US | disclosed |