Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 1/20 | 0.53 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | TDO2 | P48775 | 1/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.40 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2390807 | 0.79 | ACP3 (0.56) | ACP3IDO1TDO2P2RX7OPRM1 | |
| SCHEMBL30705308 | 0.79 | P2RX7 (0.50) | ACP3IDO1TDO2P2RX7OPRM1 | |
| SCHEMBL9242031 | 0.79 | P2RX7 (0.50) | ACP3IDO1TDO2P2RX7OPRM1 | |
| SCHEMBL4007134 | 0.78 | ACP3 (0.54) | ACP3IDO1TDO2P2RX7OPRM1 | |
| SCHEMBL29052941 | 0.78 | ACP3 (0.54) | ACP3IDO1TDO2P2RX7OPRM1 | |
| SCHEMBL3881807 | 0.77 | P2RX7 (0.48) | ACP3IDO1TDO2P2RX7OPRM1 | |
| SCHEMBL30986703 | 0.76 | ACP3 (0.57) | ACP3IDO1TDO2OPRM1OPRD1 | |
| SCHEMBL3294921 | 0.76 | ACP3 (0.57) | ACP3IDO1TDO2OPRM1OPRD1 | |
| SCHEMBL22867707 | 0.76 | ACP3 (0.53) | ACP3IDO1TDO2P2RX7OPRM1 | |
| SCHEMBL3289370 | 0.76 | ACP3 (0.57) | ACP3IDO1TDO2OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5508273-A | ARALKYLPHOSPHONATES FOR OSTEOPOROSIS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1996-04-16 | — | — | US | disclosed |