Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | CES1 | P23141 | 7/20 | 0.52 |
| ▸ | CES2 | O00748 | 6/20 | 0.52 |
| ▸ | ESR1 | P03372 | 2/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27343182 | 0.97 | ATM (0.52) | ATMCES1CES2ESR1CYP19A1 | |
| SCHEMBL9576012 | 0.88 | CES2 (0.56) | ATMCES1CES2ESR1CYP19A1 | |
| SCHEMBL8938040 | 0.88 | SMN1; SMN2 (0.61) | ATMCES1CES2ESR1CYP19A1 | |
| SCHEMBL6981701 | 0.86 | ATM (0.43) | ATMCES1CES2ESR1CYP19A1 | |
| SCHEMBL28794417 | 0.86 | TSHR (0.61) | CES1CES2MAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL11715994 | 0.86 | CES2 (0.54) | ATMCES1CES2ESR1CYP19A1 | |
| SCHEMBL27923092 | 0.82 | LOXL2 (0.50) | ATMCES1CES2ESR1CYP19A1 | |
| SCHEMBL3949381 | 0.79 | ATM (0.47) | ATMCES1CES2ESR1CYP19A1 | |
| SCHEMBL392449 | 0.78 | CES2 (0.56) | ATMCES1CES2ESR1MAPT | |
| SCHEMBL1283643 | 0.78 | CES2 (0.44) | ATMCES1CES2MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 954 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11987557-B2 | Phenalene-1-one-containing photosensitizer composition, phenalene-1-one compound and the use thereof | TRIOPTOTEC GMBH (DE) | 2024-05-21 | — | — | US | claimed |
| CN-115894881-B | Flame-retardant liquid crystal polymer with rigidity and toughness and preparation method thereof | 常州瑞杰新材料科技有限公司 | 2024-02-27 | — | — | CN | claimed |
| CN-115279875-B | Grease composition | 出光兴产株式会社 | 2024-01-12 | — | — | CN | claimed |
| CN-113490734-B | Grease composition | 出光兴产株式会社 | 2023-08-01 | — | — | CN | claimed |
| CN-113490733-B | Grease composition, and method and device for lubricating sliding mechanism using same | 出光兴产株式会社 | 2023-07-28 | — | — | CN | claimed |
| CN-113508171-B | Grease composition | 出光兴产株式会社 | 2023-06-06 | — | — | CN | claimed |
| CN-113348234-B | Grease composition | 出光兴产株式会社 | 2023-03-21 | — | — | CN | claimed |
| CN-112639060-B | Grease composition for constant velocity joints | 出光兴产株式会社 | 2022-12-09 | — | — | CN | claimed |
| US-20200087259-A1 | PHENALENE-1-ONE-CONTAINING PHOTOSENSITIZER COMPOSITION, PHENALENE-1-ONE COMPOUND AND THE USE THEREOF | TRIOPTOTEC GMBH (DE) | 2020-03-19 | — | — | US | claimed |
| WO-2017161145-A1 | TRIAZOLOPYRIDINE INHIBITORS OF MYELOPEROXIDASE AND/OR EPX | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-09-21 | — | — | WO | claimed |
| WO-1997009973-A2 | PERIPHERALLY ACTIVE ANTI-HYPERALGESIC OPIATES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1997-03-20 | — | — | WO | claimed |
| WO-1996023791-A1 | BRIDGED INDOLES AS MATRIX METALLOPROTEASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1996-08-08 | — | — | WO | claimed |
| EP-0682663-A1 | 4-HYDROXY-BENZOPYRAN-2-ONES AND 4-HYDROXY-CYCLOALKYL B]PYRAN-2-ONES USEFUL TO TREAT RETROVIRAL INFECTIONS | PHARMACIA & UPJOHN COMPANY (US) | 1995-11-22 | — | — | EP | claimed |
| WO-1995007901-A1 | SUBSTITUTED TETRONIC ACIDS USEFUL FOR TREATING HIV AND OTHER RETROVIRUSES | THE UPJOHN COMPANY (US) | 1995-03-23 | — | — | WO | claimed |
| WO-1994018188-A1 | 4-HYDROXY-BENZOPYRAN-2-ONES AND 4-HYDROXY-CYCLOALKYL[B]PYRAN-2-ONES USEFUL TO TREAT RETROVIRAL INFECTIONS | THE UPJOHN COMPANY (US) | 1994-08-18 | — | — | WO | claimed |
| US-5288905-A | Glycyl urea derivatives as anti-convulsants | G. D. SEARLE & CO. (US) | 1994-02-22 | — | — | US | claimed |
| US-4578382-A | ANTIARRHYTHMIA AGENTS | ETABLISSEMENTS NATIVELLE S.A. (FR) | 1986-03-25 | — | — | US | claimed |
| US-4419490-A | GROUP 8 METAL | HEYL & CO. CHEMISCH-PHARMAZEUTISCHE FABRIK (DE) | 1983-12-06 | — | — | US | claimed |
| US-4304684-A | Novel trialkyl aluminum cocatalyst | EXXON RESEARCH & ENGINEERING CO. (US) | 1981-12-08 | — | — | US | claimed |
| EP-0015762-A1 | Ziegler type catalyst composition | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1980-09-17 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200087259-A1 | PHENALENE-1-ONE-CONTAINING PHOTOSENSITIZER COMPOSITION, PHENALENE-1-ONE COMPOUND AND THE USE THEREOF | PYCR1, CRY1, PPOX | ATM 1689/4885CES1 2088/4885CES2 2278/4885 |
| US-11987557-B2 | Phenalene-1-one-containing photosensitizer composition, phenalene-1-one compound and the use thereof | PYCR1, CRY1, PPOX | ATM 1689/4885CES1 2088/4885CES2 2278/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.