Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 3/20 | 0.34 |
| ▸ | NOS2 | P35228 | 3/20 | 0.34 |
| ▸ | NOS3 | P29474 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7358858 | 0.94 | HTR6 (0.34) | NOS1NOS2NOS3PTGS1 | |
| SCHEMBL8835559 | 0.80 | GRM2 (0.38) | KDM4E | |
| SCHEMBL11504128 | 0.80 | DDB1 (0.42) | MEN1KMT2AALDH1A1NOS1NOS2 | |
| SCHEMBL3544624 | 0.77 | L3MBTL1 (0.49) | KDM4EMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL7175798 | 0.77 | TAAR1 (0.37) | KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL5534036 | 0.76 | HRH2 (0.41) | MEN1KMT2AALDH1A1NOS1NOS2 | |
| SCHEMBL7700085 | 0.72 | CHRNB4 (0.41) | MEN1KMT2AALDH1A1NOS1NOS2 | |
| SCHEMBL6367893 | 0.71 | CHRNB4 (0.35) | MEN1KMT2AALDH1A1NOS1NOS2 | |
| SCHEMBL576359 | 0.71 | CHRNB4 (0.35) | MEN1KMT2AALDH1A1NOS1NOS2 | |
| SCHEMBL4618385 | 0.71 | SLC18A3 (0.39) | MEN1KMT2AALDH1A1NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5508273-A | ARALKYLPHOSPHONATES FOR OSTEOPOROSIS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1996-04-16 | — | — | US | disclosed |