Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | KCNN4 | O15554 | 5/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | EDNRB | P24530 | 1/20 | 0.38 |
| ▸ | EDNRA | P25101 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4561507 | 0.81 | CYP2D6 (0.50) | MAPTKMT2AHTTCYP2D6KCNN4 | |
| SCHEMBL21644502 | 0.80 | KMT2A (0.48) | MAPTKMT2AHTTCYP2D6KCNN4 | |
| SCHEMBL2424437 | 0.79 | KIF11 (0.41) | MAPTKMT2ACYP2D6CYP1A2KCNN4 | |
| SCHEMBL4769815 | 0.78 | KMT2A (0.47) | MAPTKMT2AHTTCYP2D6CYP1A2 | |
| SCHEMBL9256005 | 0.76 | KMT2A (0.44) | MAPTKMT2AHTTCYP2D6CYP1A2 | |
| Hydrochloric Acid SCHEMBL15141831 | 0.76 | KMT2A (0.44) | MAPTKMT2AHTTCYP2D6KCNN4 | |
| SCHEMBL4557331 | 0.76 | MAPT (0.44) | MAPTKMT2AHTTCYP2D6CYP1A2 | |
| SCHEMBL5509050 | 0.76 | MAPT (0.44) | MAPTKMT2AHTTCYP2D6CYP1A2 | |
| SCHEMBL5509055 | 0.75 | MAPT (0.43) | MAPTKMT2AHTTCYP2D6CYP1A2 | |
| Bromide SCHEMBL5138481 | 0.75 | MAPT (0.43) | MAPTKMT2AHTTCYP2D6CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5502078-A | Chemical compounds | ZENECA LIMITED (GB) | 1996-03-26 | — | — | US | disclosed |