Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H3 | Q13133 | 4/20 | 0.51 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | PNMT | P11086 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ACP3 | P15309 | 1/20 | 0.40 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.39 |
| ▸ | CETP | P11597 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8938121 | 0.83 | NR1H3 (0.51) | NR1H3TRPM8EPHX1MEN1KMT2A | |
| SCHEMBL5347609 | 0.81 | NR1H3 (0.64) | NR1H3TRPM8MEN1KMT2APNMT | |
| SCHEMBL5347613 | 0.81 | NR1H3 (0.64) | NR1H3TRPM8MEN1KMT2APNMT | |
| Hydrochloric Acid SCHEMBL8938094 | 0.76 | PNMT (0.49) | EPHX1MEN1KMT2APNMTKDM4E | |
| SCHEMBL6539998 | 0.73 | RORC (0.42) | NR1H3TRPM8MEN1KMT2AKDM4E | |
| SCHEMBL6540005 | 0.73 | RORC (0.42) | NR1H3TRPM8MEN1KMT2AKDM4E | |
| SCHEMBL10822323 | 0.72 | PNMT (0.49) | NR1H3TRPM8EPHX1PNMTACP3 | |
| SCHEMBL10822325 | 0.72 | PNMT (0.49) | NR1H3TRPM8EPHX1PNMTACP3 | |
| SCHEMBL22817596 | 0.72 | CNR2 (0.58) | TRPM8MEN1KMT2APNMTKDM4E | |
| SCHEMBL22817603 | 0.72 | CNR2 (0.58) | TRPM8MEN1KMT2APNMTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5502078-A | Chemical compounds | ZENECA LIMITED (GB) | 1996-03-26 | — | — | US | disclosed |