Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H3 | Q13133 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PNMT | P11086 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | ACP3 | P15309 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5347613 | 0.83 | NR1H3 (0.64) | NR1H3MEN1KMT2AMAPTPNMT | |
| SCHEMBL5347609 | 0.83 | NR1H3 (0.64) | NR1H3MEN1KMT2AMAPTPNMT | |
| SCHEMBL8938115 | 0.83 | NR1H3 (0.51) | NR1H3MEN1KMT2APNMTKDM4E | |
| Hydrochloric Acid SCHEMBL8938103 | 0.79 | ALOX15 (0.48) | MEN1KMT2AMAPTPNMTKDM4E | |
| SCHEMBL6539998 | 0.73 | RORC (0.42) | NR1H3MEN1KMT2AMAPTKDM4E | |
| SCHEMBL6540005 | 0.73 | RORC (0.42) | NR1H3MEN1KMT2AMAPTKDM4E | |
| SCHEMBL22817596 | 0.72 | CNR2 (0.58) | MEN1KMT2APNMTKDM4EALDH1A1 | |
| SCHEMBL22817597 | 0.72 | CNR2 (0.58) | MEN1KMT2APNMTKDM4EALDH1A1 | |
| SCHEMBL22817603 | 0.72 | CNR2 (0.58) | MEN1KMT2APNMTKDM4EALDH1A1 | |
| SCHEMBL30034816 | 0.72 | CNR2 (0.58) | MEN1KMT2APNMTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5502078-A | Chemical compounds | ZENECA LIMITED (GB) | 1996-03-26 | — | — | US | disclosed |