Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.37 |
| ▸ | KCNA5 | P22460 | 4/20 | 0.37 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.35 |
| ▸ | DRD1 | P21728 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8938333 | 1.00 | CHRNA7 (0.42) | CHRNA7LMNACYP2D6CYP1A2CYP2C19 | |
| SCHEMBL1802065 | 0.81 | CYP3A4 (0.52) | CHRNA7LMNACYP2D6CYP1A2CYP2C19 | |
| SCHEMBL8938188 | 0.81 | CHRNA7 (0.62) | CHRNA7LMNACYP2D6CYP1A2CYP2C19 | |
| SCHEMBL8938184 | 0.81 | CHRNA7 (0.62) | CHRNA7LMNACYP2D6CYP1A2CYP2C19 | |
| Hydrochloric Acid SCHEMBL7654483 | 0.79 | CYP3A4 (0.50) | CHRNA7LMNACYP2D6CYP1A2CYP2C19 | |
| SCHEMBL28042294 | 0.79 | CYP2D6 (0.50) | CHRNA7LMNACYP2D6CYP1A2CYP2C19 | |
| SCHEMBL5765318 | 0.74 | IDO1 (0.56) | CHRNA7LMNACYP2D6CYP1A2CYP2C19 | |
| Carbamic Acid SCHEMBL17460309 | 0.72 | GAA (0.47) | LMNACYP2D6CYP1A2CYP2C19CYP3A4 | |
| SCHEMBL9353293 | 0.72 | SLC6A3 (0.45) | LMNACYP2D6CYP1A2CYP2C19CYP3A4 | |
| SCHEMBL1788903 | 0.71 | ESR1 (0.39) | LMNACYP1A2CYP2C19CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5534626-A | SELECTIVE MUSCARINIC RECEPTOR ANTAGONIST INTERMEDIATES | PFIZER INC. (US) | 1996-07-09 | — | — | US | disclosed |
| US-5410046-A | Selective muscarinic receptor antagonists | PFIZER INC. (US) | 1995-04-25 | — | — | US | disclosed |
| US-5231104-A | Anticholinergic | PFIZER INC. (US) | 1993-07-27 | — | — | US | disclosed |
| EP-0350309-B1 | PIPERIDINE DERIVATIVES | Pfizer Limited (GB) | 1992-11-11 | — | — | EP | disclosed |
| US-5089505-A | Anticholinergic agents | PFIZER INC. (US) | 1992-02-18 | — | — | US | disclosed |
| EP-0350309-A1 | Piperidine derivatives | Pfizer Limited (GB) | 1990-01-10 | — | — | EP | disclosed |