Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.43 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.43 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8938208 | 0.95 | IDO1 (0.45) | SLC6A3SLC6A4SLC6A2KCNH2MEN1 | |
| SCHEMBL1802065 | 0.89 | CYP3A4 (0.52) | SLC6A3SLC6A4SLC6A2CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL7654483 | 0.87 | CYP3A4 (0.50) | SLC6A3SLC6A4SLC6A2CYP1A2CYP3A4 | |
| SCHEMBL28042294 | 0.87 | CYP2D6 (0.50) | SLC6A3SLC6A4SLC6A2CYP1A2CYP3A4 | |
| Carbamic Acid SCHEMBL17460309 | 0.79 | GAA (0.47) | CYP1A2CYP3A4CYP2D6CYP2C19CYP2C9 | |
| SCHEMBL5859624 | 0.77 | CYP1A2 (0.47) | SLC6A3SLC6A4SLC6A2CYP1A2CYP3A4 | |
| SCHEMBL8938188 | 0.76 | CHRNA7 (0.62) | SLC6A3SLC6A4SLC6A2CYP1A2CYP3A4 | |
| SCHEMBL8938184 | 0.76 | CHRNA7 (0.62) | SLC6A3SLC6A4SLC6A2CYP1A2CYP3A4 | |
| SCHEMBL16226328 | 0.75 | ACHE (0.63) | SLC6A3SLC6A4SLC6A2CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL7440651 | 0.74 | ACHE (0.61) | SLC6A3SLC6A4SLC6A2CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0399414-B1 | Piperidine derivative, method for preparation thereof, and a pharmaceutical composition comprising the same | HOKURIKU PHARMACEUTICAL (JP) | 1994-09-21 | — | — | EP | disclosed |
| US-5153207-A | Antihistamine and antiallergic agent | HOKURIKU PHARMACEUTICAL CO., LTD. (JP) | 1992-10-06 | — | — | US | disclosed |
| EP-0399414-A1 | Piperidine derivative, method for preparation thereof, and a pharmaceutical composition comprising the same | HOKURIKU PHARMACEUTICAL CO., LTD. (JP) | 1990-11-28 | — | — | EP | disclosed |