Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PREP | P48147 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8938600 | 0.87 | MEN1 (0.45) | MAPTF2HCRTR1HCRTR2 | |
| SCHEMBL8938431 | 0.85 | PREP (0.47) | MAPTLMNAPREP | |
| SCHEMBL8938442 | 0.84 | PKM (0.42) | MAPTPREP | |
| SCHEMBL8938625 | 0.80 | MEN1 (0.40) | F2 | |
| SCHEMBL8938630 | 0.79 | PREP (0.42) | MAPTPREP | |
| SCHEMBL8938395 | 0.79 | FAAH (0.43) | PREP | |
| SCHEMBL8938389 | 0.75 | PREP (0.59) | MAPTLMNAPREP | |
| SCHEMBL8938499 | 0.74 | MEN1 (0.48) | PREPF2 | |
| SCHEMBL8079479 | 0.73 | PREP (0.55) | MAPTLMNAPREP | |
| SCHEMBL8938473 | 0.72 | PREP (0.56) | PREPF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5547978-A | ENDOPEPTIDASE INHIBITORS | MEIJI SEIKA KAISHA, LTD. (JP) | 1996-08-20 | — | — | US | claimed |
| US-5547978-A | ENDOPEPTIDASE INHIBITORS | MEIJI SEIKA KAISHA, LTD. (JP) | 1996-08-20 | — | — | US | disclosed |