Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | HTR7 | P34969 | 2/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8938625 | 0.88 | MEN1 (0.40) | MEN1KMT2ANPC1RAB9AF2 | |
| SCHEMBL8938536 | 0.87 | MAPT (0.41) | F2MAPTHCRTR1HCRTR2 | |
| SCHEMBL8938499 | 0.85 | MEN1 (0.48) | MEN1KMT2ANPC1RAB9AF2 | |
| SCHEMBL8938389 | 0.83 | PREP (0.59) | KMT2ARAB9AALDH1A1MAPT | |
| SCHEMBL8938677 | 0.82 | MEN1 (0.43) | MEN1KMT2ANPC1RAB9AF2 | |
| SCHEMBL8938617 | 0.81 | DAGLA (0.49) | MEN1KMT2ANPC1RAB9AF2 | |
| SCHEMBL8938620 | 0.81 | PLA2G4A (0.48) | MEN1KMT2ANPC1RAB9AF2 | |
| SCHEMBL8938580 | 0.81 | MEN1 (0.50) | MEN1KMT2ANPC1RAB9AF2 | |
| SCHEMBL8938439 | 0.80 | MEN1 (0.50) | MEN1KMT2ANPC1RAB9APKM | |
| SCHEMBL8938534 | 0.80 | DAGLA (0.49) | MEN1KMT2ANPC1RAB9AF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5547978-A | ENDOPEPTIDASE INHIBITORS | MEIJI SEIKA KAISHA, LTD. (JP) | 1996-08-20 | — | — | US | claimed |
| JP-6227980-A | — | — | None | — | — | JP | disclosed |
| US-5547978-A | ENDOPEPTIDASE INHIBITORS | MEIJI SEIKA KAISHA, LTD. (JP) | 1996-08-20 | — | — | US | disclosed |
| JP-H06227980-A | PYRROLIDIN-2-YLCARBONYL HETEROCYCLIC COMPOUND DERIVATIVE | MEIJI SEIKA KAISHA LTD | 1994-08-16 | — | — | JP | disclosed |