Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 6/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA9 | Q16790 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7632252 | 0.86 | — | — | |
| SCHEMBL10306546 | 0.74 | CA1 (0.33) | ACHEGRM5CA1CA2CA9 | |
| SCHEMBL18050322 | 0.74 | ALDH1A1 (0.58) | ALDH1A1CYP2A6ACHETDP1GRM5 | |
| SCHEMBL18050324 | 0.74 | ALDH1A1 (0.58) | ALDH1A1CYP2A6ACHETDP1GRM5 | |
| SCHEMBL2246279 | 0.73 | ALDH1A1 (0.50) | ALDH1A1CYP2A6TDP1HSD17B10TSHR | |
| SCHEMBL2240955 | 0.73 | CA1 (0.50) | ALDH1A1ACHETDP1CA1CA2 | |
| SCHEMBL406538 | 0.72 | — | — | |
| SCHEMBL219074 | 0.67 | ALDH1A1 (0.58) | ALDH1A1CYP2A6ACHETDP1GRM5 | |
| SCHEMBL9445826 | 0.67 | GRM5 (0.64) | ALDH1A1CYP2A6ACHETDP1GRM5 | |
| SCHEMBL4457730 | 0.67 | GRM5 (0.64) | ALDH1A1CYP2A6ACHETDP1GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112142587-B | Acetophenone acid and preparation method and application thereof | 长沙嘉桥生物科技有限公司 | 2023-05-12 | — | — | CN | disclosed |
| US-20110201661-A1 | Spiro Derivatives of Parthenin as Novel Anticancer Agents | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2011-08-18 | — | — | US | disclosed |
| WO-2011070136-A1 | IODINE RADIOLABELLING METHOD | GE HEALTHCARE LIMITED (GB) | 2011-06-16 | — | — | WO | disclosed |
| US-5488106-A | Process for preparing 6-[(isoxazolinyl)methyl]penicillanic acid 1,1-dioxide compounds | AMERICAN CYANAMID COMPANY (US) | 1996-01-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110201661-A1 | Spiro Derivatives of Parthenin as Novel Anticancer Agents | CDK10, NEK10, AKR1B10 | ALDH1A1 1855/4885CYP2A6 2024/4885ACHE 3450/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.