Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PREP | P48147 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8938600 | 0.82 | MEN1 (0.45) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL2841931 | 0.79 | HPGD (0.46) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL2841930 | 0.79 | HPGD (0.46) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL7297456 | 0.75 | MEN1 (0.49) | MEN1KMT2ANPC1RAB9APREP | |
| SCHEMBL7297462 | 0.75 | MEN1 (0.49) | MEN1KMT2ANPC1RAB9APREP | |
| SCHEMBL9879640 | 0.74 | MEN1 (0.57) | MEN1KMT2ANPC1RAB9APREP | |
| SCHEMBL7302362 | 0.73 | MEN1 (0.45) | MEN1KMT2ANPC1RAB9APREP | |
| SCHEMBL7302355 | 0.73 | MEN1 (0.45) | MEN1KMT2ANPC1RAB9APREP | |
| SCHEMBL6285952 | 0.73 | PREP (0.65) | MEN1KMT2ANPC1RAB9APREP | |
| SCHEMBL6285958 | 0.73 | PREP (0.65) | MEN1KMT2ANPC1RAB9APREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5547978-A | ENDOPEPTIDASE INHIBITORS | MEIJI SEIKA KAISHA, LTD. (JP) | 1996-08-20 | — | — | US | disclosed |