Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 6/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8938395 | 0.87 | FAAH (0.43) | FAAHCES1NCEH1 | |
| SCHEMBL8938415 | 0.83 | MEN1 (0.49) | MEN1NPC1RAB9AKMT2AF2 | |
| SCHEMBL8938596 | 0.82 | FAAH (0.56) | FAAHCES1MEN1NPC1RAB9A | |
| SCHEMBL8938534 | 0.81 | DAGLA (0.49) | FAAHCES1MEN1NPC1RAB9A | |
| SCHEMBL8938612 | 0.81 | MEN1 (0.47) | MEN1NPC1RAB9AKMT2AF2 | |
| SCHEMBL8938520 | 0.81 | MEN1 (0.47) | MEN1NPC1RAB9AKMT2AFKBP1A | |
| SCHEMBL8938620 | 0.81 | PLA2G4A (0.48) | CES1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL8938447 | 0.80 | ACE (0.51) | MEN1NPC1RAB9AKMT2AFKBP1A | |
| SCHEMBL8938580 | 0.80 | MEN1 (0.50) | MEN1NPC1RAB9AKMT2AF2 | |
| SCHEMBL8938439 | 0.79 | MEN1 (0.50) | CES1MEN1NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5547978-A | ENDOPEPTIDASE INHIBITORS | MEIJI SEIKA KAISHA, LTD. (JP) | 1996-08-20 | — | — | US | claimed |
| US-5547978-A | ENDOPEPTIDASE INHIBITORS | MEIJI SEIKA KAISHA, LTD. (JP) | 1996-08-20 | — | — | US | disclosed |