Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 5/20 | 0.50 |
| ▸ | ESR1 | P03372 | 9/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 7/20 | 0.49 |
| ▸ | STS | P08842 | 4/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.49 |
| ▸ | PGR | P06401 | 4/20 | 0.49 |
| ▸ | AR | P10275 | 4/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.49 |
| ▸ | HTR2B | P41595 | 3/20 | 0.49 |
| ▸ | SERPINA6 | P08185 | 3/20 | 0.49 |
| ▸ | SNCA | P37840 | 3/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.49 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.49 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29500480 | 0.95 | ESR1 (0.53) | SHBGESR1ESR2STSHSD17B10 | |
| SCHEMBL8959369 | 0.95 | ESR1 (0.53) | SHBGESR1ESR2STSHSD17B10 | |
| SCHEMBL514373 | 0.95 | ESR1 (0.53) | SHBGESR1ESR2STSHSD17B10 | |
| SCHEMBL8938753 | 0.87 | LMNA (0.51) | ESR1ESR2STSHSD17B10LMNA | |
| Benzoic Acid SCHEMBL9628348 | 0.85 | STS (0.47) | SHBGESR1ESR2STSHSD17B10 | |
| SCHEMBL9627672 | 0.81 | LMNA (0.55) | ESR1ESR2STSHSD17B10LMNA | |
| SCHEMBL8959365 | 0.79 | ESR1 (0.52) | SHBGESR1ESR2STSHSD17B10 | |
| SCHEMBL8959381 | 0.79 | ESR1 (0.52) | SHBGESR1ESR2STSHSD17B10 | |
| SCHEMBL259537 | 0.79 | ESR1 (0.52) | SHBGESR1ESR2STSHSD17B10 | |
| SCHEMBL9146993 | 0.79 | ESR1 (0.52) | SHBGESR1ESR2STSHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5491137-A | TREATING ESTROGEN DEFICIENCY | SCHERING AKTIENGESELLSCHAFT (DE) | 1996-02-13 | — | — | US | claimed |
| EP-0511727-B1 | 14-alpha,17alpha-(propano- and 17,2-propeno)-estratrienes | SCHERING AG (DE) | 1995-11-15 | — | — | EP | claimed |
| EP-0511727-A1 | 14-alpha,17alpha-(propano- and 17,2-propeno)-estratrienes | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-11-04 | — | — | EP | claimed |