Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | LAP3 | P28838 | 2/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CETP | P11597 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | UBE2N | P61088 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6139849 | 0.90 | OPRM1 (0.41) | OPRM1SPHK1CYP2D6LMNATP53 | |
| SCHEMBL9791846 | 0.89 | FAAH (0.42) | SPHK1CYP2D6LMNATP53GMNN | |
| SCHEMBL19032541 | 0.84 | OPRM1 (0.44) | OPRM1SPHK1CYP2D6LMNATP53 | |
| SCHEMBL28247753 | 0.84 | OPRM1 (0.44) | OPRM1SPHK1CYP2D6LMNATP53 | |
| SCHEMBL19032634 | 0.84 | OPRM1 (0.44) | OPRM1SPHK1CYP2D6LMNATP53 | |
| SCHEMBL23407456 | 0.84 | OPRM1 (0.44) | OPRM1SPHK1CYP2D6LMNATP53 | |
| SCHEMBL15234071 | 0.84 | OPRM1 (0.44) | OPRM1SPHK1CYP2D6LMNATP53 | |
| SCHEMBL29153559 | 0.82 | OPRM1 (0.46) | OPRM1SPHK1CYP2D6LMNATP53 | |
| SCHEMBL21627258 | 0.82 | OPRM1 (0.46) | OPRM1SPHK1CYP2D6LMNATP53 | |
| SCHEMBL23358953 | 0.81 | OPRM1 (0.50) | OPRM1SPHK1CYP2D6LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0681566-A4 | -g(a)-AMINONITRILES DERIVED FROM FATTY ALKYL ALKYLENE DIAMINES. | AKZO NOBEL NV (NL) | 1996-04-17 | — | — | EP | disclosed |
| US-5476960-A | αaminonitriles derived from reaction of carbonyl compounds and fatty aklyl alkylene diamines | AKZO NOBEL N.V. (NL) | 1995-12-19 | — | — | US | disclosed |
| EP-0681566-A1 | $g(a)-AMINONITRILES DERIVED FROM FATTY ALKYL ALKYLENE DIAMINES | Akzo Nobel N.V. (NL) | 1995-11-15 | — | — | EP | disclosed |
| US-5374762-A | α-aminomononitriles containing fatty alkyl C12 to C22 group | AKZO NOBEL N.V. (NL) | 1994-12-20 | — | — | US | disclosed |
| US-5374763-A | Surfactants | AKZO NOBEL N.V. (NL) | 1994-12-20 | — | — | US | disclosed |
| US-5371265-A | α-aminodinitriles containing fatty alkyl C12 to C22 group | AKZO NOBEL N.V. (NL) | 1994-12-06 | — | — | US | disclosed |
| WO-1994017031-A1 | α-AMINONITRILES DERIVED FROM FATTY ALKYL ALKYLENE DIAMINES | AKZO N.V. (NL) | 1994-08-04 | — | — | WO | disclosed |
| US-5319126-A | α-aminonitriles derived from fatty alkyl alkylene diamines | AKZO N.V. (NL) | 1994-06-07 | — | — | US | disclosed |