Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 3/20 | 0.31 |
| ▸ | S100A4 | P26447 | 1/20 | 0.31 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.30 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.30 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.30 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.30 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL301080 | 0.82 | TDP1 (0.34) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL301081 | 0.82 | TSHR (0.41) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL25356732 | 0.80 | GPR35 (0.36) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL28545972 | 0.80 | ALDH1A1 (0.36) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL8011546 | 0.74 | ALDH1A1 (0.44) | TDP1ALDH1A1CYP3A4MEN1KMT2A | |
| SCHEMBL7513494 | 0.74 | ALDH1A1 (0.48) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL9357685 | 0.73 | ALDH1A1 (0.32) | TDP1ALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL240574 | 0.70 | TDP1 (0.52) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL14880530 | 0.70 | ALDH1A1 (0.46) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL8877797 | 0.69 | ALDH1A1 (0.46) | TDP1ALDH1A1HIF1ACYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108290860-B | Iminotetrahydropyrimidinone derivatives as PLASMEPSIN V inhibitors | UCB生物制药有限责任公司 | 2021-08-10 | — | — | CN | disclosed |
| US-5484762-A | Aryloxy-n-(substituted phenyl) benzotriazole herbicidal agents | AMERICAN CYANAMID COMPANY (US) | 1996-01-16 | — | — | US | disclosed |