Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.40 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | TDP2 | O95551 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16913126 | 0.79 | METAP1 (0.43) | LMNAKDM4EMAPTCYP3A4TDP2 | |
| SCHEMBL16913303 | 0.77 | CHEK1 (0.45) | KDM4EPDE10AMAPTHTT | |
| SCHEMBL17020946 | 0.76 | ESR1 (0.44) | LMNAKDM4EMAPTCYP3A4BACE1 | |
| SCHEMBL18602248 | 0.71 | BACE1 (0.51) | LMNAALDH1A1KDM4ECYP3A4ABCB1 | |
| SCHEMBL8938835 | 0.70 | CYP3A4 (0.58) | LMNAALDH1A1KDM4EPDE10AMAPT | |
| SCHEMBL17625718 | 0.69 | BACE1 (0.63) | LMNAALDH1A1KDM4ECYP3A4ABCB1 | |
| SCHEMBL7981630 | 0.69 | MAPT (0.75) | ALDH1A1KDM4EMAPTCYP3A4ABCB1 | |
| SCHEMBL16913220 | 0.69 | CYP11B2 (0.56) | ALDH1A1KDM4ECYP3A4CYP19A1HPGD | |
| SCHEMBL8938825 | 0.69 | ALDH1A1 (0.44) | LMNAALDH1A1KDM4EMAPTCYP3A4 | |
| SCHEMBL6961118 | 0.68 | CHEK1 (0.80) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5543298-A | ADDING SPECIFIED COMPOUND TO LIQUID SAMPLE, MEASURING RATE OF AUTOOXIDATION SPECTROPHOTOMETRICALLY | OXIS INTERNATIONAL S.A. (FR) | 1996-08-06 | — | — | US | disclosed |
| EP-0625209-A1 | METHOD FOR ASSAYING THE SOD ACTIVITY BY USING A SELF-OXIDIZABLE COMPOUND NECESSARY FOR ITS IMPLEMENTATION, SELF-OXIDIZABLE COMPOUNDS AND PREPARATION THEREOF. | BIOXYTECH (FR) | 1994-11-23 | — | — | EP | disclosed |
| WO-1993011258-A1 | METHOD FOR ASSAYING THE SOD ACTIVITY BY USING A SELF-OXIDIZABLE COMPOUND NECESSARY FOR ITS IMPLEMENTATION, SELF-OXIDIZABLE COMPOUNDS AND PREPARATION THEREOF | BIOXYTECH (FR) | 1993-06-10 | — | — | WO | disclosed |