Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 4/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20710739 | 0.92 | LTA4H (0.49) | LTA4HDRD2DRD3L3MBTL1TDP1 | |
| SCHEMBL8939021 | 0.85 | CA4 (0.43) | LTA4HDRD2DRD4DRD3CA4 | |
| SCHEMBL2938616 | 0.83 | LTA4H (0.47) | LTA4HL3MBTL1HPGDTDP1TP53 | |
| SCHEMBL8939002 | 0.81 | CA4 (0.47) | LTA4HDRD2DRD4DRD3CA4 | |
| SCHEMBL11209432 | 0.78 | LTA4H (0.43) | LTA4HL3MBTL1TDP1TP53 | |
| SCHEMBL15417421 | 0.77 | CA2 (0.36) | LTA4HCA4HPGDTDP1 | |
| SCHEMBL2929963 | 0.76 | LTA4H (0.46) | LTA4HDRD2DRD3MAPTKCNH2 | |
| SCHEMBL2937814 | 0.76 | LTA4H (0.46) | LTA4HDRD2DRD3MAPTKCNH2 | |
| SCHEMBL21403902 | 0.76 | LTA4H (0.46) | LTA4HDRD2DRD3MAPTKCNH2 | |
| SCHEMBL11153747 | 0.76 | LTA4H (0.46) | LTA4HDRD2DRD3MAPTKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5498741-A | Alkyl aryl arylphosphonites, process for the preparation thereof and use thereof | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-03-12 | — | — | US | disclosed |